Protein Overview: S12A3_RAT

General Information:
Name(s) found:	S12A3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|33563368\|ref\|NP_062218.2\| solute carrier family 12, member 3 [Rattus norvegicus] [NCBI NR] gi\|27151789\|sp\|P55018.2\|S12A3_RAT RecName: Full=Solute carrier family 12 member 3; AltName: Full=Thiazide-sensitive sodium-chloride cotransporter; AltName: Full=Na-Cl symporter [NCBI NR] gi\|22389599\|gb\|AAA21252.2\| thiazide-sensitive sodium-chloride cotransporter [Rattus norvegicus] [NCBI NR] Solute carrier family 12 member 3 OS=Rattus norvegicus GN=Slc12a3 PE=2 SV=2 [Swiss-Prot] (P55018) Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter) [Swiss-Prot] solute carrier family 12, member 3; thiazide-sensitive Na-Cl cotransporter [HMR_022704-rand.fasta] solute carrier family 12, member 3 [Rattus norvegicus]gi\|22389599\|gb\|AAA21252.2\| thiazide-sensitive sodium-chloride cotransporter [Rattus norvegicus]gi\|27151789\|sp\|P55018\|S123_RAT Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cot [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Solute carrier family 12 member 3 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Solute carrier family 12, member 3 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Solute carrier family 12 member 3 (Thiazide-sensitive sodium-chloride cotransporter) (Na-Cl symporter) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] thiazide-sensitive sodium-chloride cotransporter [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SOLUTE CARRIER FAMILY 12 MEMBER 3 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] solute carrier family 12, member 3 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Slc12a3 Solute carrier family 12 member 3 [rat-ipi-250309-contam.fasta] Solute carrier family 12 member 3 OS=Rattus norvegicus GN=Slc12a3 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1002 amino acids
Gene Ontology:
Cellular Component:	integral to membrane [IEA] cytosol [IEA] vesicle [IDA] plasma membrane [IEA] apical plasma membrane [IDA][ISS]
Biological Process:	sodium ion transport [IDA][IMP][ISS] ion transport [IEA] transmembrane transport [IEA] chloride transport [IMP]
Molecular Function:	sodium:chloride symporter activity [IDA][IMP] symporter activity [IEA] transporter activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAELPVTEMP GDALCSGRFT ISTLLGGDEP PPAACDNSQP SHLTHGSTLY LRTFGYNTID  60
   61 VVPAYEHYAN SALPGEPRKV RPTLADLHSF LKQEGSHLHA LAFDGRPGHE LTDGLVEDET 120
  121 GANSEKSPGE PVRFGWVKGV MIRCMLNIWG VILYLRLPWI TAQAGIVLTW LIILLSVMVT 180
  181 SITGLSISAI STNGKVKSGG TYFLISRSLG PELGGSIGLI FAFANAVGVA MHTVGFAETV 240
  241 RDLLQENGTP IVDPINDIRI IGVVTVTVLL AISLAGMEWE SKAQVLFFLV IMVSFANYLV 300
  301 GTLIPASKDK ASKGFYSYHG DIFVQNLVPD WRGIDGSFFG MFSIFFPSAT GILAGANISG 360
  361 DLKDPAVAIP KGTLMAIFWT TISYLAISAT IGSCVVRDAS GDVNDTITPG PGLCEGLACG 420
  421 YGWNFTECSQ QHSCRYGLIN YYQTMSMVSA FAPLITAGIF GATLSSALAC LVSAAKVFQC 480
  481 LCEDQLYPLI GFFGKGYGKN KEPVRGYLLA YAIAVAFIII AELNTIAPII SNFFLCSYAL 540
  541 INFSCFHASI TNSPGWRPSF RYYSKWAALF GAVISVVIMF LLTWWAALIA IGVVLFLLLY 600
  601 VIYKKPEVNW GSSVQAGSYN LALSYSVGLN EVEDHIKNYR PQCLVLTGPP NFRPALVDFV 660
  661 STFTQNLSLM ICGHVLIAPG KQRVPELRLI ASGHTKWLNK RKIKAFYSDV IAEDLRSGVQ 720
  721 ILMQASGLGR MKPNILVVGF KKNWQSAHPA TLEDYIGILH DAFDFNYGVC IMRMREGLNV 780
  781 SEALQTHTAP EALVQEEQTS TIFQSEQGKK TIDIYWLFDD GGLTLLIPYL LHRKKRWGKC 840
  841 KIRVFVGGQI NRMDEERKAI ISLLSKFRLG FHEVHVLPDI NQKPQVEHTK RFEDMIAPFR 900
  901 LNDGFKDEAT VAEMRRDYPW KISDEEINKN RIKSLRQVRL NEILLDYSRD AALIILTLPI 960
  961 GRKGKCPSSL YMAWLETLSQ DLSPPVLLIR GNQENVLTFY CQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: S12A3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: