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Protein Overview: RLUC_ECOLI

General Information:
Name(s) found: RLUC_ECOLI [Swiss-Prot]
Description(s) found:
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  • gi|76363884|sp|P0AA39.1|RLUC_ECOLI RecName: Full=Ribosomal large subunit pseudouridine synthase C; AltName: Full=rRNA-uridine isomerase C; AltName: Full=rRNA pseudouridylate synthase C [NCBI NR]
  • pir||C64852 probable pseudouridylate synthase yceC - Escherichia coli (strain K-12) [NCBI NR]
  • Ribosomal large subunit pseudouridine synthase C (EC 5.4.99.-) (rRNA-uridine isomerase C) (rRNA pseudouridylate synthase C) - Escherichia coli [Swiss-Prot]
  • 23S rRNA pseudouridylate synthase; Ribosomal large subunit pseudouridine synthase C [Escherichia coli K12]gi|30062620|ref|NP_836791.1| hypothetical protein S1170 [Shigella flexneri 2a str. 2457T]gi|24112492|ref|NP_707002.1| hypothetical protein SF1090 [ [nrdb_11152004_Chlamydomonas]
  • Ribosomal large subunit pseudouridine synthase C (rRNA-uridine isomerase C) (rRNA pseudouridylate synthase C) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Ribosomal large subunit pseudouridine synthase C OS=Escherichia coli (strain K12) GN=rluC PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 319 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTETPSVKI VAITADEAGQ RIDNFLRTQL KGVPKSMIYR ILRKGEVRVN KKRIKPEYKL  60
   61 EAGDEVRIPP VRVAEREEEA VSPHLQKVAA LADVILYEDD HILVLNKPSG TAVHGGSGLS 120
  121 FGVIEGLRAL RPEARFLELV HRLDRDTSGV LLVAKKRSAL RSLHEQLREK GMQKDYLALV 180
  181 RGQWQSHVKS VQAPLLKNIL QSGERIVRVS QEGKPSETRF KVEERYAFAT LVRCSPVTGR 240
  241 THQIRVHTQY AGHPIAFDDR YGDREFDRQL TEAGTGLNRL FLHAAALKFT HPGTGEVMRI 300
  301 EAPMDEGLKR CLQKLRNAR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..79] FFAS03 3.03 Structure of the catalytic domain of 23S rRNA pseudouridine synthase RluD
    2 View Details [80..319] PSI-BLAST 64.0 Crystal structure of the catalytic domain of E. coli pseudouridine synthase RluC

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  4.91262436325473 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  4.03380803526801 bayes_pls_golite062009
  • isomerase activity
    		•  2.9653842461049 bayes_pls_golite062009
  • catalytic activity
    		•  2.2317719900989 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle