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Protein Overview: PDE2_DICDI

General Information:
Name(s) found: PDE2_DICDI [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • 3',5'-cyclic-nucleotide phosphodiesterase regA OS=Dictyostelium discoideum GN=regA PE=1 SV=1 [Swiss-Prot]
    • Organism: Dictyostelium discoideum
    Length: 793 amino acids

    Gene Ontology:
    Cellular Component: intracellular [TAS]
    Biological Process: regulation of release of sequestered calcium ion into cytosol [IMP]
    cAMP metabolic process [IMP]
    multicellular organismal development [IMP]
    two-component signal transduction system (phosphorelay) [IEA]
    response to osmotic stress [TAS]
    regulation of transcription, DNA-dependent [IEA]
    cAMP catabolic process [IDA]
    positive regulation of release of sequestered calcium ion into cytosol [IMP]
    negative regulation of lateral pseudopodium assembly [IMP]
    sorocarp development [IMP]
    response to stimulus [IEA]
    sporulation resulting in formation of a cellular spore [IMP]
    Molecular Function: [NOT]3',5'-cyclic-GMP phosphodiesterase activity [IDA]
    3',5'-cyclic-AMP phosphodiesterase activity [IDA][IMP]
    two-component response regulator activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNKQEEIDQ FLSSTSTSPS PSSSSSPSNN DSTSLKSMIS GIENLNVHSK GNDNKNNNNN  60
   61 NNNNNSNNNE KQKDIVSLEN NSSSNNTTTT TTTTTTSNHN SNNNSNNNNN NINNNNINNN 120
  121 NYEPLVNGHN NGFGDKLNDQ PSPSSHRVSD FSDEYSPSKV RILVADDDDV QRKILNNLLK 180
  181 KFHYNVTLVP NGEIAWEYIN KGQQKYDLVL TDVMMPHITG FDLLQRINDH PVHRHIPVIL 240
  241 MSGTAVDYKY ANDTIKIGGQ DFLTKPIAKE LLKKKIDTVL QSIWQRRKEE EYKATLAQER 300
  301 EKGNKLAKEM ELKEHEIEEL TKKVSKMSSI SKEAMESPLV SVTRNIEELL KQSSWSHYES 360
  361 EIKEKLSSIL KELGSSNIYR PSFEKLIKND SVDPVTKSFL VSEFSSTTSR RNSIPTFPQT 420
  421 TYNRDTKEVI KGWEFDVFKY SEDDLMPLLV DMFENFQLPE IFKIPIEKLQ RFIMTVNALY 480
  481 RKNNRYHNFT HAFDVTQTVY TFLTSFNAAQ YLTHLDIFAL LISCMCHDLN HPGFNNTFQV 540
  541 NAQTELSLEY NDISVLENHH AMLTFKILRN SECNILEGLN EDQYKELRRS VVQLILATDM 600
  601 QNHFEHTNKF QHHLNNLPFD RNKKEDRQMI LNFLIKCGDI SNIARPWHLN FEWSLRVSDE 660
  661 FFQQSHYETI CGYPVTPFMD KTKTTRARIA ADFIDFVASP LFQSMAKFLK ESQFLLKVIS 720
  721 KNRENWQAYM ELQKEGKCND DDLQFMEDPT ILVKSKLPKI DEEENRDKVS SSSSSSTAPL 780
  781 TSTSSSNNET SSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle