YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: PFN1

General Information:
Name(s) found: PFN1 [HGNC (HUGO)]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • profilin 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 139 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGWNAYIDNL MADGTCQDAA IVGYKDSPSV WAAVPGKTFV NITPAEVGVL VGKDRSSFYV  60
   61 NGLTLGGQKC SVIRDSLLQD GEFSMDLRTK STGGAPTFNV TVTKTDKTLV LLMGKEGVHG 120
  121 GLINKKCYEM ASHLRRSQY

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. PFN1 gi|112491310 gi|13786858 gi|14277752, gi|... gi|150261449 gi|162330234, gi... gi|576245, gi|57...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..139] PSI-BLAST 47.0 Profilin (actin-binding protein)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  7.981958446142 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  6.51470611165788 bayes_pls_golite062009
  • actin monomer binding
    		•  3.80837480536839 bayes_pls_golite062009
  • binding
    		•  3.26636517628678 bayes_pls_golite062009
  • phosphatidylinositol-4,5-bisphosphate binding
    		•  3.08913463974786 bayes_pls_golite062009
  • protein binding
    		•  2.14534188091242 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle