Protein Overview: PLCB2_RAT

General Information:
Name(s) found:	PLCB2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|3688530\|emb\|CAA09465.1\| phospholipase C beta 2 [Rattus norvegicus] [NCBI NR] gi\|32699411\|sp\|O89040.1\|PLCB2_RAT RecName: Full=1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2; AltName: Full=Phospholipase C-beta-2; Short=PLC-beta-2 [NCBI NR] gi\|16758232\|ref\|NP_445930.1\| phospholipase C, beta 2 [Rattus norvegicus] [NCBI NR] 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 OS=Rattus norvegicus GN=Plcb2 PE=2 SV=1 [Swiss-Prot] (O89040) 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (EC 3.1.4.11) (PLC-beta-2) (Phospholipase C-beta-2) [Swiss-Prot] phospholipase C beta 2; PKC beta II [HMR_022704-rand.fasta] phospholipase C, beta 2 [Rattus norvegicus]gi\|3688530\|emb\|CAA09465.1\| phospholipase C beta 2 [Rattus norvegicus]gi\|32699411\|sp\|O89040\|PIB2_RAT 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (PLC-beta-2) (Phospholipase C-beta-2) [nrdb_11152004_Chlamydomonas] (NM_053478) phospholipase C beta 2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 (Phospholipase C-beta-2) (PLC-beta-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phospholipase C, beta 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phospholipase C beta 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2 (Phospholipase C-beta-2) (PLC-beta-2) [nr-271106-contam.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform 1 of 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 OS=Rattus norvegicus GN=Plcb2 [011711_HMR.fasta] 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 OS=Rattus norvegicus GN=Plcb2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1183 amino acids
Gene Ontology:
Cellular Component:	cytosol [UNKNOWN][IDA] Golgi apparatus [IDA] plasma membrane [IDA]
Biological Process:	intracellular signaling pathway [IDA] signal transduction [IEA] lipid metabolic process [IEA] phospholipid catabolic process [NAS] lipid catabolic process [IEA] sensory perception of bitter taste [UNKNOWN] detection of chemical stimulus involved in sensory perception of bitter taste [IDA][IMP]
Molecular Function:	phosphoinositide phospholipase C activity [IEA][NAS] protein binding [IDA] phospholipase C activity [IMP] calcium ion binding [IEA] phospholipid binding [IDA] signal transducer activity [IDA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLLNPVLLP PKVKAYLSQG ERFIKWDDET SIASPVILRV DPKGYYLYWT HQSKEMEFLD  60
   61 VTSIRDTRFG KFAKIPKSQK LREVFNMDFP DNHFLLKTFT VVSGPDMVGL TFHNFVSYKE 120
  121 NVGKDWAEDV LALAKHPMTA NASRSTFLDK ILVKLKMQLS PEGKIPVKNF FQMFPADRKR 180
  181 VEAALSACHL AKGKNDAINP EDFPESVYKS FLMSLCPRPE IDEIFTSYHA KAKPYMTKEH 240
  241 LTKFINQKQR DPRLNSLLFP PARPEQVQAL IDKYEPSGIN VQRGQLSPEG MVWFLCGPEN 300
  301 SVLAHDTLRI HQDMTQPLNH YFINSSHNTY LTAGQFSGPS SAEMYRQVLL SGCRCVELDC 360
  361 WKGKPPDEEP IITHGFTMTT DILFKEAVEA IAESAFKTSP YPVILSFENH VDSPRQQAKM 420
  421 AEYCRTMFGE TLLTEPLENF PLKPGMPLPS PEDLRGKILI KNKKNQFSGP ASPNKKPDGV 480
  481 SEGGFPSSVP VEEDTGWTAE DRTEVEEGEE EEEVEEEEEE ESGNLDEEEI KKMQSDEGTA 540
  541 GLEVTAYEEM SSLVNYIQPT KFISFEFSAQ KNRSYLVSSF TELKAYELLS KASMQFVDYN 600
  601 KRQMSRVYPK GTRMDSSNYM PQMFWNAGCQ MVALNFQTMD LPMQQNMALF EFNGQSGYLL 660
  661 KHEFMRRQDK QFNPFSVDRI DVVVATTLSI TVISGQFLSE RSVRTYVEVE LFGLPGDPKR 720
  721 RYRTKLSPTA NSINPVWKEE PFIFEKILVP ELASLRIAVM EEGGKFIGHR IIPINALHSG 780
  781 YHHLCLRSES NMPLTMPALF VFLEMKDYVP DTWADLTVAL ANPIKYFSAH DKKSVKLKEV 840
  841 TGSLPEKLFS GIPVASQSNG APVSAGNGST APGTKAKEEA TKEVAEPQTT SLEELRELKG 900
  901 VVKLQRRHEK ELRELERRGA RRWEELLQRG AAQLAELQDP AASCKLRPGK GSRKKRIVPC 960
  961 EETIVVPREV LEGPDPRVQD LKDRLEQELQ QQGEEQYRSV LKRKEQHVTE QIAKMMELAR1020
 1021 EKQAAELKSF KETSETDTKE MKKKLEAKRL ERIQAMTKVT TDKVAQERLK REINNSHIQE1080
 1081 VVQAVKQMTE TLERHQEKLE EKQTACLEQI QAMEKQFQEK ALAEYEAKMK GLEAEVKESM1140
 1141 RACFKACFPT EAEEKPERPC EASEESCPQE PLVNKTDTQE SRL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: PLCB2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: