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Protein Overview: PDXK_SHEEP

General Information:
Name(s) found: PDXK_SHEEP [Swiss-Prot]
Description(s) found:
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  • gi|7387989|sp|P82197.1|PDXK_SHEEP RecName: Full=Pyridoxal kinase; AltName: Full=Pyridoxine kinase [NCBI NR]
  • gi|71042033|pdb|1YHJ|A Chain A, Crystal Structure Of Pyridoxal Kinase In Complex With Roscovitine And Derivatives [NCBI NR]
  • gi|71042032|pdb|1YGK|A Chain A, Crystal Structure Of Pyridoxal Kinase In Complex With Roscovitine And Derivatives [NCBI NR]
  • gi|71042031|pdb|1YGJ|A Chain A, Crystal Structure Of Pyridoxal Kinase In Complex With Roscovitine And Derivatives [NCBI NR]
  • gi|48425328|pdb|1RFV|B Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Adp [NCBI NR]
  • gi|48425327|pdb|1RFV|A Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Adp [NCBI NR]
  • gi|48425326|pdb|1RFU|H Chain H, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425325|pdb|1RFU|G Chain G, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425324|pdb|1RFU|F Chain F, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425323|pdb|1RFU|E Chain E, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425322|pdb|1RFU|D Chain D, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425321|pdb|1RFU|C Chain C, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425320|pdb|1RFU|B Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425319|pdb|1RFU|A Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [NCBI NR]
  • gi|48425318|pdb|1RFT|A Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Amp- Pcp And Pyridoxamine [NCBI NR]
  • gi|28948485|pdb|1LHR|B Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Atp [NCBI NR]
  • gi|28948484|pdb|1LHR|A Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Atp [NCBI NR]
  • gi|28948483|pdb|1LHP|B Chain B, Crystal Structure Of Pyridoxal Kinase From Sheep Brain [NCBI NR]
  • gi|28948482|pdb|1LHP|A Chain A, Crystal Structure Of Pyridoxal Kinase From Sheep Brain [NCBI NR]
  • Pyridoxal kinase OS=Ovis aries GN=PDXK PE=1 SV=1 [Swiss-Prot]
  • Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Adpgi|48425327|pdb|1RFV|A Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Adpgi|48425326|pdb|1RFU|H Chain H, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plpgi| [nrdb_11152004_Chlamydomonas]
  • Chain A, Crystal Structure Of Pyridoxal Kinase From Sheep Brain [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Atp [nr-271106-contam.fasta]
  • Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Atp [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of Pyridoxal Kinase In Complex With Roscovitine And Derivatives [nr-271106-contam.fasta]
  • Pyridoxal kinase (Pyridoxine kinase) [nr-271106-contam.fasta]
  • Chain C, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain G, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain B, Crystal Structure Of Pyridoxal Kinase From Sheep Brain [nr-271106-contam.fasta]
  • Chain H, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Amp- Pcp And Pyridoxamine [nr-271106-contam.fasta]
  • Chain F, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain A, Crystal Structure Of Pyridoxal Kinase Complexed With Adp [nr-271106-contam.fasta]
  • Chain E, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
  • Chain B, Crystal Structure Of Pyridoxal Kinase Complexed With Adp [nr-271106-contam.fasta]
  • Chain D, Crystal Structure Of Pyridoxal Kinase Complexed With Adp And Plp [nr-271106-contam.fasta]
    • Organism: Ovis aries
    Length: 312 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEECRVLSI QSHVVRGYVG NRAATFPLQV LGFEVDAVNS VQFSNHTGYS HWKGQVLNSD  60
   61 ELQELYDGLK LNHVNQYDYV LTGYTRDKSF LAMVVDIVQE LKQQNPRLVY VCDPVMGDQR 120
  121 NGEGAMYVPD DLLPVYREKV VPVADIITPN QFEAELLTGR KIHSQEEALE VMDMLHSMGP 180
  181 DTVVITSSNL LSPRGSDYLM ALGSQRTRAP DGSVVTQRIR MEMHKVDAVF VGTGDLFAAM 240
  241 LLAWTHKHPN NLKVACEKTV SAMHHVLQRT IKCAKAKSGE GVKPSPAQLE LRMVQSKKDI 300
  301 ESPEIVVQAT VL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..312] PSI-BLAST 69.39794 Pyridoxal kinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lithium ion binding
    		•  3.00550221878163 bayes_pls_golite062009
  • sodium ion binding
    		•  2.93046843966773 bayes_pls_golite062009
  • kinase activity
    		•  2.74755351135221 bayes_pls_golite062009
  • pyridoxal kinase activity
    		•  2.62798458074822 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.43969902311075 bayes_pls_golite062009
  • transferase activity
    		•  2.15883296431019 bayes_pls_golite062009
  • phosphomethylpyrimidine kinase activity
    		•  2.12104666683074 bayes_pls_golite062009
  • pyridoxal binding
    		•  2.04719269680858 bayes_pls_golite062009
  • catalytic activity
    		•  1.74474587246986 bayes_pls_golite062009
  • binding
    		•  1.4216897826135 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.37866801006693 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  1.32862180479506 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.23363144435362 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.21529398967164 bayes_pls_golite062009
  • potassium ion binding
    		•  1.18018952731159 bayes_pls_golite062009
  • alkali metal ion binding
    		•  1.18018952731159 bayes_pls_golite062009
  • DNA binding
    		•  0.954497955488766 bayes_pls_golite062009
  • transcription factor activity
    		•  0.376784274163604 bayes_pls_golite062009
  • protein binding
    		•  0.117280046908929 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle