YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FBpp0300514, Moe-PJ

General Information:
Name(s) found: FBpp0300514 [FlyBase]
Moe-PJ / FBpp0089236 [FlyBase]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • type=protein; loc=X:complement(8767980..8768144,8768222..8768434,8768536..8768932,8769127..8769893,8770606..8770785,8774325..8774339); ID=FBpp0300514; name=Moe-PL; parent=FBgn0011661,FBtr0308194; dbxref=FlyBase:FBpp0300514,FlyBase_Annotation_IDs:CG10701-PL,REFSEQ:NP_001245584,GB_protein:AFH07298; MD5=4fcd824dc6f0f440606c356a8c45bf67; length=578; release=r5.56; species=Dmel; [FlyBase]
  • The gene Moesin is referred to in FlyBase by the symbol Dmel\Moe (CG10701, FBgn0011661). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:8767636..8792343. It has the cytological map location 8B4-8B6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: determination of left/right symmetry; olfactory behavior; oocyte anterior/posterior axis specification; actin cytoskeleton organization; establishment or maintenance of epithelial cell apical/basal polarity; establishment or maintenance of polarity of larval imaginal disc epithelium; rhabdomere membrane biogenesis; rhabdomere development; regulation of actin cytoskeleton organization; regulation of membrane potential in photoreceptor cell. 84 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: adult segment; organ system; adult mesothoracic segment; thoracic segment; adult; imaginal precursor; developing anatomical structure; embryonic hindgut; dorsal thoracic disc; external compound sense organ. It has 10 annotated transcripts and 10 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 578 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    adherens junction [NAS]
    subapical complex [TAS]
    cytoplasm [IDA][NAS]
    cell cortex [IDA]
    spindle [IDA]
    [NOT]fusome [IDA]
    extrinsic to membrane [IEA]
    actin filament [IDA]
    plasma membrane [IDA][NAS]
    Biological Process: establishment or maintenance of apical/basal cell polarity [TAS]
    cytoskeleton organization [TAS]
    rhabdomere membrane biogenesis [IMP]
    protein localization [TAS]
    anterior/posterior pattern formation [TAS]
    eye photoreceptor cell development [TAS]
    pole plasm assembly [TAS]
    olfactory behavior [IMP]
    determination of left/right symmetry [IMP]
    oocyte anterior/posterior axis specification [IMP]
    actin filament-based process [NAS]
    pole plasm protein localization [TAS]
    regulation of actin cytoskeleton organization [IMP]
    rhabdomere development [IMP]
    morphogenesis of an epithelium [TAS]
    establishment or maintenance of epithelial cell apical/basal polarity [IMP]
    regulation of membrane potential in photoreceptor cell [IDA]
    actin cytoskeleton organization [IMP]
    establishment or maintenance of polarity of larval imaginal disc epithelium [IMP]
    Molecular Function: protein binding [IPI]
    actin binding [NAS]
    cytoskeletal protein binding [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSPKALNVRV TTMDAELEFA IQSTTTGKQL FDQVVKTIGL REVWFFGLQY TDSKGDSTWI  60
   61 KLYKKVMNQD VKKENPLQFR FRAKFYPEDV AEELIQDITL RLFYLQVKNA ILTDEIYCPP 120
  121 ETSVLLASYA VQARHGDHNK TTHTAGFLAN DRLLPQRVID QHKMSKDEWE QSIMTWWQEH 180
  181 RSMLREDAMM EYLKIAQDLE MYGVNYFEIR NKKGTDLWLG VDALGLNIYE QDDRLTPKIG 240
  241 FPWSEIRNIS FSEKKFIIKP IDKKAPDFMF FAPRVRINKR ILALCMGNHE LYMRRRKPDT 300
  301 IDVQQMKAQA REEKNAKQQE REKLQLALAA RERAEKKQQE YEDRLKQMQE DMERSQRDLL 360
  361 EAQDMIRRLE EQLKQLQAAK DELELRQKEL QAMLQRLEEA KNMEAVEKLK LEEEIMAKQM 420
  421 EVQRIQDEVN AKDEETKRLQ DEVEDARRKQ VIAAEAAAAL LAASTTPQHH HVAEDENENE 480
  481 EELTNGDAGG DVSRDLDTDE HIKDPIEDRR TLAERNERLH DQLKALKQDL AQSRDETKET 540
  541 ANDKIHRENV RQGRDKYKTL REIRKGNTKR RVDQFENM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..578] PSI-BLAST 82.221849 No description for 2i1jA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle