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Protein Overview: CXCL2_RAT

General Information:
Name(s) found: CXCL2_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • C-X-C motif chemokine 2 OS=Rattus norvegicus GN=Cxcl2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 100 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [UNKNOWN][IEA]
    extracellular region [IEA]
    Biological Process: chemotaxis [IEA]
    inflammatory response [IEA]
    immune response [IEA]
    neutrophil chemotaxis [IMP]
    leukocyte chemotaxis [IMP]
    Molecular Function: chemokine activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPPTRQLLN AVLVLLLLLA TNHQGTGVVV ASELRCQCLT TLPRVDFKNI QSLTVTPPGP  60
   61 HCAQTEVIAT LKDGHEVCLN PEAPLVQRIV QKILNKGKAN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 15.69897 Macrophage inflammatory protein-2

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytokine activity
    		•  8.07273475133641 bayes_pls_golite062009
  • chemokine activity
    		•  7.19574940007631 bayes_pls_golite062009
  • chemokine receptor binding
    		•  7.19574940007631 bayes_pls_golite062009
  • G-protein-coupled receptor binding
    		•  7.12866319987718 bayes_pls_golite062009
  • receptor binding
    		•  5.6737526433068 bayes_pls_golite062009
  • interleukin-8 receptor binding
    		•  3.11139680462527 bayes_pls_golite062009
  • chemoattractant activity
    		•  3.05299139114464 bayes_pls_golite062009
  • binding
    		•  2.73164240332813 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  2.45155021423769 bayes_pls_golite062009
  • protein binding
    		•  2.40339234127151 bayes_pls_golite062009
  • heparin binding
    		•  2.14306964280471 bayes_pls_golite062009
  • pattern binding
    		•  1.02739535268516 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.8745248884958 bayes_pls_golite062009
  • CCR chemokine receptor binding
    		•  0.697359799598971 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.49941396747283 bayes_pls_golite062009
  • CCR2 chemokine receptor binding
    		•  0.0620912591294003 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle