Protein Overview: LGALS7

General Information:
Name(s) found:	LGALS7 [HGNC (HUGO)]
Description(s) found: SHOW ONLY BEST	gi\|3891558\|pdb\|1BKZ\|B Chain B, Crystal Structure Of Human Galectin-7 [NCBI NR] gi\|3891557\|pdb\|1BKZ\|A Chain A, Crystal Structure Of Human Galectin-7 [NCBI NR] gi\|3891505\|pdb\|2GAL\|B Chain B, Crystal Structure Of Human Galectin-7 In Complex With Galactose [NCBI NR] gi\|3891504\|pdb\|2GAL\|A Chain A, Crystal Structure Of Human Galectin-7 In Complex With Galactose [NCBI NR] gi\|3891482\|pdb\|5GAL\|B Chain B, Crystal Structure Of Human Galectin-7 In Complex With N- Acetyllactosamine [NCBI NR] gi\|3891481\|pdb\|5GAL\|A Chain A, Crystal Structure Of Human Galectin-7 In Complex With N- Acetyllactosamine [NCBI NR] gi\|3891480\|pdb\|4GAL\|B Chain B, Crystal Structure Of Human Galectin-7 In Complex With Lactose [NCBI NR] gi\|3891479\|pdb\|4GAL\|A Chain A, Crystal Structure Of Human Galectin-7 In Complex With Lactose [NCBI NR] gi\|3891471\|pdb\|3GAL\|B Chain B, Crystal Structure Of Human Galectin-7 In Complex With Galactosamine [NCBI NR] gi\|3891470\|pdb\|3GAL\|A Chain A, Crystal Structure Of Human Galectin-7 In Complex With Galactosamine [NCBI NR] lectin, galactoside-binding, soluble, 7 [HGNC (HUGO)] (P47929) Galectin-7 (Gal-7) (HKL-14) (PI7) (p53-induced protein 1) [Swiss-Prot] Chain B, Crystal Structure Of Human Galectin-7 In Complex With N-Acetyllactosaminegi\|3891481\|pdb\|5GAL\|A Chain A, Crystal Structure Of Human Galectin-7 In Complex With N-Acetyllactosaminegi\|3891480\|pdb\|4GAL\|B Chain B, Crystal Structure Of Human Galectin- [nrdb_11152004_Chlamydomonas] Tax_Id=9606 Galectin-7 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta] Chain B, Crystal Structure Of Human Galectin-7 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain A, Crystal Structure Of Human Galectin-7 [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain B, Crystal Structure Of Human Galectin-7 In Complex With Galactose [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain A, Crystal Structure Of Human Galectin-7 In Complex With Galactose [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain B, Crystal Structure Of Human Galectin-7 In Complex With N- Acetyllactosamine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain A, Crystal Structure Of Human Galectin-7 In Complex With N- Acetyllactosamine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain B, Crystal Structure Of Human Galectin-7 In Complex With Lactose [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain A, Crystal Structure Of Human Galectin-7 In Complex With Lactose [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain B, Crystal Structure Of Human Galectin-7 In Complex With Galactosamine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain A, Crystal Structure Of Human Galectin-7 In Complex With Galactosamine [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta] Chain B, Crystal Structure Of Human Galectin-7 In Complex With N-Acetyllactosamine [nr-271106-contam.fasta] Chain A, Crystal Structure Of Human Galectin-7 In Complex With N-Acetyllactosamine [nr-271106-contam.fasta]
Organism:	Homo sapiens
Length:	135 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	NONE FOUND
Molecular Function:	NONE FOUND

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 SNVPHKSSLP EGIRPGTVLR IRGLVPPNAS RFHVNLLCGE EQGSDAALHF NPRLDTSEVV 60 61 FNSKEQGSWG REERGPGVPF QRGQPFEVLI IASDDGFKAV VGDAQYHHFR HRLPLARVRL 120 121 VEVGGDVQLD SVRIF

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Noble WS, et al. (2009) Manuscript in preparation.		LGALS7 gi\|219109210, gi...

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..135]	PSI-BLAST	44.0	S-lectin, different isoforms

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
sugar binding	3.34064405064299	bayes_pls_golite062009
glycosaminoglycan binding	2.70103238455595	bayes_pls_golite062009
binding	2.40096962515027	bayes_pls_golite062009
polysaccharide binding	2.35851723238763	bayes_pls_golite062009
monosaccharide binding	2.09529521879228	bayes_pls_golite062009
carbohydrate binding	1.90829797790335	bayes_pls_golite062009
protein binding	1.80794638640093	bayes_pls_golite062009
heparin binding	1.60966215355794	bayes_pls_golite062009
extracellular matrix binding	1.41229380365824	bayes_pls_golite062009
fibronectin binding	1.10309233016451	bayes_pls_golite062009
galactoside binding	1.08479183125487	bayes_pls_golite062009
pattern binding	0.969915174528009	bayes_pls_golite062009
receptor binding	0.9012250808046	bayes_pls_golite062009
extracellular matrix structural constituent	0.5068011550246	bayes_pls_golite062009
transcription regulator activity	0.372701974560119	bayes_pls_golite062009
nucleic acid binding	0.216086300988177	bayes_pls_golite062009
DNA binding	0.157628282318248	bayes_pls_golite062009
growth factor activity	0.119475011376319	bayes_pls_golite062009
fibroblast growth factor 2 binding	0.0714976455077903	bayes_pls_golite062009
fibrinogen binding	0.0714976455077903	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

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