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Protein Overview: LACI_ECOLI

General Information:
Name(s) found: LACI_ECOLI [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Lactose operon repressor - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 360 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPVTLYDVA EYAGVSYQTV SRVVNQASHV SAKTREKVEA AMAELNYIPN RVAQQLAGKQ  60
   61 SLLIGVATSS LALHAPSQIV AAIKSRADQL GASVVVSMVE RSGVEACKAA VHNLLAQRVS 120
  121 GLIINYPLDD QDAIAVEAAC TNVPALFLDV SDQTPINSII FSHEDGTRLG VEHLVALGHQ 180
  181 QIALLAGPLS SVSARLRLAG WHKYLTRNQI QPIAEREGDW SAMSGFQQTM QMLNEGIVPT 240
  241 AMLVANDQMA LGAMRAITES GLRVGADISV VGYDDTEDSS CYIPPLTTIK QDFRLLGQTS 300
  301 VDRLLQLSQG QAVKGNQLLP VSLVKRKTTL APNTQTASPR ALADSLMQLA RQVSRLESGQ 360
  361

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..360] PSI-BLAST 90.522879 Lac repressor (LacR), N-terminal domain; Lac-repressor (lacR) core (C-terminal domain)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  3.56046382984539 bayes_pls_golite062009
  • DNA binding
    		•  2.83896385348242 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.80027597752699 bayes_pls_golite062009
  • transcription factor activity
    		•  2.66587775072853 bayes_pls_golite062009
  • binding
    		•  2.28053989162516 bayes_pls_golite062009
  • transporter activity
    		•  0.69447727045719 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  0.613419400163686 bayes_pls_golite062009
  • receptor activity
    		•  0.581432737510315 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.537625088427333 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.244777496593902 bayes_pls_golite062009
  • protein binding
    		•  0.186782087158009 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.1760601003859 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.00441561491566994 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle