Protein Overview: ACVL1_RAT

General Information:
Name(s) found:	ACVL1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|609588\|gb\|AAC37705.1\| serine-threonine kinase receptor type I [Rattus norvegicus] [NCBI NR] gi\|52789247\|gb\|AAH83173.1\| Activin A receptor type II-like 1 [Rattus norvegicus] [NCBI NR] gi\|46397779\|sp\|P80203.2\|ACVL1_RAT RecName: Full=Serine/threonine-protein kinase receptor R3; Short=SKR3; AltName: Full=TGF-B superfamily receptor type I; Short=TSR-I; Flags: Precursor [NCBI NR] gi\|1589364\|prf\|\|2211223A type I receptor Ser/Thr kinase [NCBI NR] gi\|149032001\|gb\|EDL86913.1\| activin A receptor type II-like 1, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|149032000\|gb\|EDL86912.1\| activin A receptor type II-like 1, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|149031999\|gb\|EDL86911.1\| activin A receptor type II-like 1, isoform CRA_b [Rattus norvegicus] [NCBI NR] gi\|11967973\|ref\|NP_071886.1\| activin A receptor type II-like 1 [Rattus norvegicus] [NCBI NR] (P80203) Serine/threonine-protein kinase receptor R3 precursor (EC 2.7.1.37) (SKR3) (TGF-B superfamily receptor type I) (TSR-I) [Swiss-Prot] Serine/threonine-protein kinase receptor R3 OS=Rattus norvegicus GN=Acvrl1 PE=1 SV=2 [Swiss-Prot] activin A receptor type II-like 1; Activin receptor like kinase 1 [HMR_022704-rand.fasta] activin A receptor type II-like 1 [Rattus norvegicus]gi\|52789247\|gb\|AAH83173.1\| Activin A receptor type II-like 1 [Rattus norvegicus]gi\|46397779\|sp\|P80203\|KIR3_RAT Serine/threonine-protein kinase receptor R3 precursor (SKR3) (TGF-B superfamily receptor [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Serine/threonine-protein kinase receptor R3 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_022441) activin receptor like kinase 1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Serine/threonine-protein kinase receptor R3 precursor (SKR3) (TGF-B superfamily receptor type I) (TSR-I) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] activin A receptor type II-like 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] activin A receptor type II-like 1, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Activin A receptor type II-like 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serine-threonine kinase receptor type I [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] type I receptor Ser/Thr kinase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SERINE/THREONINE-PROTEIN KINASE RECEPTOR R3 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Acvrl1 Serine/threonine-protein kinase receptor R3 [rat-ipi-250309-contam.fasta] Serine/threonine-protein kinase receptor R3 OS=Rattus norvegicus GN=Acvrl1 [011711_HMR.fasta] Serine/threonine-protein kinase receptor R3 OS=Rattus norvegicus GN=Acvrl1 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	504 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [UNKNOWN] dendrite [IDA] membrane [IEA] integral to membrane [IEA] neuronal cell body [IDA] cell surface [UNKNOWN]
Biological Process:	signal transduction [UNKNOWN] negative regulation of cell adhesion [UNKNOWN] negative regulation of cell proliferation [UNKNOWN] transforming growth factor beta receptor signaling pathway [UNKNOWN][IDA] blood circulation [UNKNOWN] positive regulation of transcription [UNKNOWN] blood vessel morphogenesis [UNKNOWN] protein heterooligomerization [IDA] protein amino acid phosphorylation [UNKNOWN][IDA][IEA][TAS] regulation of transcription [UNKNOWN] regulation of blood pressure [UNKNOWN] negative regulation of focal adhesion assembly [UNKNOWN] positive regulation of BMP signaling pathway [UNKNOWN] angiogenesis [UNKNOWN] in utero embryonic development [UNKNOWN] negative regulation of cell growth [UNKNOWN] negative regulation of endothelial cell migration [UNKNOWN] wound healing, spreading of epidermal cells [UNKNOWN] negative regulation of cell migration [UNKNOWN]
Molecular Function:	transforming growth factor beta receptor activity [UNKNOWN][IEA] protein serine/threonine kinase activity [UNKNOWN][IEA] receptor activity [IEA] transforming growth factor beta receptor activity, type I [UNKNOWN][IDA] transmembrane receptor protein serine/threonine kinase activity [TAS] nucleotide binding [IEA] transforming growth factor beta binding [UNKNOWN][TAS] ATP binding [UNKNOWN][IEA] receptor signaling protein serine/threonine kinase activity [IDA] protein binding [UNKNOWN] activin binding [UNKNOWN] SMAD binding [UNKNOWN][IDA] metal ion binding [IEA] activin receptor activity, type I [UNKNOWN] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLGIFRRVF LMLSVALGLT KGDLVKPSRG QLVNCTCENP HCKRPICQGA WCTVVLVREQ  60
   61 GRHPQVYRGC GSLNQELCLG RPTEFVNHHC CYRSFCNHNV SLMLEATQTP SEEPEVDAHL 120
  121 PLILGPVLAL LVLVALGTLG LWRVRRRQEK QRGLHSDLGE SSLILKASEQ GDSMLGDFLV 180
  181 SDCTTGSGSG LPFLVQRTVA RQVALVECVG KGRYGEVWRG SWHGESVAVK IFSSRDEQSW 240
  241 FRETEIYNTV LLRHDNILGF IASDMTSRNS STQLWLITHY HEHGSLYDFL QRQTLEPQLA 300
  301 LRLAVSAACG LAHLHVEIFG TQGKPAIAHR DLKSRNVLVK SNLQCCIADL GLAVMHSQSS 360
  361 DYLDIGNNPR VGTKRYMAPE VLDEQIRTDC FESYKWTDIW AFGLVLWEIA RRTIINGIVE 420
  421 DYRPPFYDMV PNDPSFEDMK KVVCVDQQTP TIPNRLAADP VLSGLAQMMR ECWYPNPSAR 480
  481 LTALRIKKTL QKLSQNPEKP KVIH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACVL1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: