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Protein Overview: CkIIbeta-PE

General Information:
Name(s) found: CkIIbeta-PE / FBpp0089135 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene Casein kinase II Ã?&#142;Ã?² subunit is referred to in FlyBase by the symbol Dmel\CkIIÃ?&#142;Ã?² (CG15224, FBgn0000259). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:11686569..11694097. It has the cytological map location 10E3. There is experimental evidence that it has the molecular function</span>: protein serine/threonine kinase activity; protein kinase regulator activity. There is experimental evidence that it is involved in the biological process</span>: protein amino acid phosphorylation; locomotor rhythm; mushroom body development; circadian rhythm. 31 alleles are reported. The phenotypes of these alleles are annotated with: Kenyon cell; mushroom body; calyx of mushroom body; peripheral nervous system; ventral nerve cord commissure; longitudinal connective; wing. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 235 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    protein kinase CK2 complex [IDA][NAS]
    cytoplasm [IDA]
    cytosol [IDA]
    Biological Process: eclosion rhythm [TAS]
    mushroom body development [IMP]
    locomotor rhythm [IMP]
    protein amino acid phosphorylation [IDA][NAS]
    circadian rhythm [IMP]
    rhythmic behavior [TAS]
    Molecular Function: protein kinase activity [NAS]
    protein serine/threonine kinase activity [IDA]
    protein kinase regulator activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSEEVSWV TWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPNYRQAL DMILDLEPED  60
   61 ELEDNPLQSD MTEQAAEMLY GLIHARYILT NRGIAQMIEK YQTGDFGHCP RVYCESQPML 120
  121 PLGLSDIPGE AMVKTYCPKC IDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPT 180
  181 NQFVPRLYGF KIHSLAYQIQ LQAAANFKMP LRAQRGQPPK DEEPENNADT VPKRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] PSI-BLAST 114.0 Casein kinase II beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase regulator activity
    		•  4.14878012076359 bayes_pls_golite062009
  • kinase regulator activity
    		•  4.09603095102334 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.91779610785511 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.79245883940915 bayes_pls_golite062009
  • protein kinase activity
    		•  2.75473427458132 bayes_pls_golite062009
  • kinase activity
    		•  2.66515798949431 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.39333807060713 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  1.99491617326192 bayes_pls_golite062009
  • binding
    		•  1.85951177140712 bayes_pls_golite062009
  • transferase activity
    		•  1.77218599619559 bayes_pls_golite062009
  • protein binding
    		•  1.4657010373022 bayes_pls_golite062009
  • catalytic activity
    		•  0.2012862421225 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle