Protein Overview: gi|44888998

General Information:
Name(s) found:	gi\|44888998 [NCBI NR]
Description(s) found: Found 4 descriptions. SHOW ALL	gi\|44888998\|sp\|P29993.3\|ITPR_DROME RecName: Full=Inositol 1,4,5-trisphosphate receptor; AltName: Full=InsP3 receptor; Short=InsP3R [NCBI NR]
Organism:	Drosophila melanogaster
Length:	2838 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum membrane [NAS] membrane [IEA] endoplasmic reticulum [IDA]
Biological Process:	response to oxidative stress [IMP] transmembrane transport [IEA] mushroom body development [IMP] molting cycle, chitin-based cuticle [IGI] flight behavior [IMP] nuclear division [IDA] release of sequestered calcium ion into cytosol [IMP] stabilization of membrane potential [IGI]
Molecular Function:	inositol-1,4,5-trisphosphate receptor activity [IDA][ISS][NAS] calcium channel activity [NAS] inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDNIIGSAS FLHLGDIVSL YAEGSVCGFL STLGLVDDRT VVCPEAGDLS CPPKKFRDCL  60
   61 IKICPMNRYS AQKQFWKAAK QSASSNTDPN LLKRLHHAAE IEKKQNETEN KKLLGTSIQY 120
  121 GRAVVQLLHL KSNKYLTVNK RLPSLLEKNA MRVYLDANGN EGSWFYIKPF YKLRSIGDYV 180
  181 VVVGDKVILS PVNADQQNLH VAANYELPDN PGCKEVNVLN SSTSWKISLF MEHKENQEHI 240
  241 LKGGDVVRLF HAEQEKFLTM DEYKKQYHVF LRTTGRTSAT AATSSKALWE IEVVQHDSCR 300
  301 GGAGDWNSLY RFKHLATGHY LAAEAEIDVS AGAMSATSAS GHDLHLGDCS KDSGLSCSTM 360
  361 NSTINDKPKG KQYRLVSVPY SADIASVFVL DATTMARPDS LVPQSSYVRL QHICSNTWVH 420
  421 ATSIPIDADD DKPVMSMVCC SPIKEDKEAF ALIPVSPVEV RDLDFANDAC KVLATVTSKL 480
  481 DNGSISINER RALISLLQDI VYFIAGMENE QNKTKALEFT IKNPIRDRQK LLREQYILKQ 540
  541 LFKILQGPFQ EHTAGDGPFL RLDELSDPKN SPYKNIFRLC YRILRLSQQD YRKNQEYIAK 600
  601 HFGLMQKQIG YDILAEDTIT ALLHNNRKLL EKHITAAEIE TFVGLVRKNM HNWDSRFLDY 660
  661 LSDLCVSNRK AIAVTQELIC KSVLSDKNKD ILIETQVKAL RTGSGPVRCY KGNSEDVCLA 720
  721 TLAEDPGDDE DRSDVQSTST TTTWDSASLN EDDGTPSTGD KYEIHLKWTG QPTSRSMADL 780
  781 ASCDGGELEA AILNYYRHQL NLFSNMCLNR QYLALNELSP RLDIDLILKC MSDETMPYEL 840
  841 RASFCRLMLH LHVDRDPQEP VTPVKYARLW SEIPSKMSIQ DYDGKNQQPD QNKQACRAKF 900
  901 NTTIAFVENY LCNVATKVWL FTDQEQNKLT FEVVKLARDL IYFGFYSFSD LLRLTKTLLS 960
  961 ILDCVSDTSS GEFASTDIDS VEEETNAEAE GGVLRSIGDI NTVMTSLALG SVGQAIAAPT1020
 1021 ISLQQRKSVS QLMKEYPLVM DTKLKIIEIL QFILDVRLDY RISCLLSIFK REFDESEVAA1080
 1081 SAASNEASQQ QSQQQEPQTP GSSNETDPLD SAESVAAGAA AAAATTARQK NIDLESIGVQ1140
 1141 AEGIFDCERS DAANLDLDGQ GGRTFLRVLL HLIMHDYAPL VSGALHLLFR HFSQRQEVLQ1200
 1201 AFRQVQLLVS DSDVESYKQI KSDLDILRQS VEKSELWVYK AKATDELGAT DAGGDAVSLE1260
 1261 YNAALSQEQR NEYRKVKEIL IRMNKFCVTA SGPGSVVKPR KHEQRLLRNV GVHTVVLDLL1320
 1321 QNPYDEKDDE LMKELMCLAH EFLQNFCLGN QQNQVLLHNH LDLFLNPGIL EAKTVCAIFK1380
 1381 DNLALCNEVT DKVVQHFVHC IEIHGRHVAY LQFLQTVVAA ENQFIRRCQD MVMQELINSG1440
 1441 EDVLVFYNDK GSFNHFVQMM QQQMLGMEKL SDDSPLKYHV ELVKLLACCT MGKNVYTEIK1500
 1501 CNNLLSLDDI VTIICHPLCM PEVKEAYVDF LNHCYIDTEV EMKEIYASGH MWSLFEKSFL1560
 1561 VDINQLITNP AAASNKTLQA YVLNGVTNLL GSFFASPFSD QSAIVQSRQL IFVQLLQAAH1620
 1621 RITQCRWLSL GDRFNVENCI RTLTESAKMR SIALPPELEQ QVATMSSKTA MLTRQTTKWL1680
 1681 LASKQPKYEA QQAASLMRWD RSIIEGLQDI VSLLEDQLKP VVEAELSLLV DILYRSELLF1740
 1741 PAGTEARKRC ESGGFIRKLI KHTEKLLEEK EERMCVKVLR TLREMMAIDV NYGEKGDALR1800
 1801 QTLLLRYFQT KSTPRLPEDE VPLLAAPLMD PAKQNHLVTH GPGAKYLQRA GKTLHEMQNH1860
 1861 LDREGASDLV VELVIKSVHS PNIFVEAVEL GIALLEGGNP IIQKGMFQKF LSDDLNQAFF1920
 1921 KVFFEKMKDA QQEIKSTVTV NTTDIAAKAH EHKQDTNLEL DKIARKHGLK SNGVVITEEL1980
 1981 KRELHNAGLA TARAYGNARN IHSGEESSAI SVNSPLEDIL AEKLEKHKDS RDQRNQLSNK2040
 2041 VLVMQPILRF LQLLCENHNP DMQNLLRNQN NKTNNNLVSE TLMFLDCICG STTGGLGLLG2100
 2101 LYINEHNLAL INQTLEALTE YCQGPCHENQ NCIATHESNG LDIITALILN NINPLGENRM2160
 2161 DLVLELKNNA SKLLLAIMES RGDSENAERI LYNMNPKQLV EVACKAYHQE ELIDEQDDGD2220
 2221 EPDAGSDDDD ATVSPREVGH NIYILCHQLA QHNKELAGLL KASEDPQSAS FDAKTSQALM2280
 2281 YYATHTAQIE IVRNDRTLEQ IVFPIPEICE YLTTDTKIKI LNTAERDDQG SKLADFFDKA2340
 2341 EEMFNEMKWQ KKLRSQPLLF WISSYMSLWS NILFNCVVVI NMIVAFFYPF DNTVPELSSH2400
 2401 ISLLFWIITI FSLVIVLALP RESGIRTFIG SVILRFIFLL GPESTLCLLG VVTVTLKSVH2460
 2461 IVSIMGNKGT LEKQLIKIIT DFQLLYHCIY IAFCFCGLIF HPFFYSLLLF DVVYREETLV2520
 2521 NVIRSVTRNG RSIVLTAVLA LILVYLFSII GYMFFKDDFL VSVDFEEQDN APPPSVPLTL2580
 2581 SVPVSGDSCS APDDLGNCQA AKEVAPPSAG GGEVKERSCD SLVMCIVTTL NQGLRNGGGI2640
 2641 GDILRAPSSK EGLFVARVIY DLLFFFIVII IVLNLIFGVI IDTFADLRSE KQQKEAILKT2700
 2701 TCFICSLNRS AFDNKTVSFE EHIKSEHNMW HYLYFIVLVK VKDPTEFTGP ESYVYAMVKA2760
 2761 GILEWFPRLR AMSLAAVDAD GEQIELRSMQ AQLLDTQLLI KNLSTQLHEL KDHMTEQRKQ2820
 2821 KQRLGLLNTT ANSLLPFQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: gi|44888998

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: