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Protein Overview: otp-PE

General Information:
Name(s) found: otp-PE / FBpp0288728 [FlyBase]
Description(s) found:
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  • gi|229462936|sp|P56672.2|OTP_DROME RecName: Full=Homeobox protein orthopedia [NCBI NR]
  • gi|221330466|ref|NP_001097388.2| orthopedia, isoform E [Drosophila melanogaster] [NCBI NR]
  • gi|220902308|gb|AAS64751.3| orthopedia, isoform E [Drosophila melanogaster] [NCBI NR]
  • gi|134085567|gb|ABO52842.1| IP17664p [Drosophila melanogaster] [NCBI NR]
  • Homeobox protein orthopedia OS=Drosophila melanogaster GN=otp PE=2 SV=2 [Swiss-Prot]
  • The gene orthopedia is referred to in FlyBase by the symbol Dmel\otp (CG10036, FBgn0015524). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16771116..16790900. It has the cytological map location 57B4. There is experimental evidence that it has the molecular function</span>: DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: regulation of transcription. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • type=protein; loc=2R:complement(16771997..16772266,16772707..16772873,16773786..16773911,16774028..16774232,16783216..16783350,16783980..16784275,16789533..16789563); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728, [fly-100309-contam.fasta]
  • type=protein; loc=2R:complement(16771997..16772266,16772707..16772873,16773786..16773911,16774028..16774232,16783216..16783350,16783980..16784275,16789533..16789563); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(16771997..16772266,16772707..16772873,16773786..16773911,16774028..16774232,16783216..16783350,16783980..16784275,16789533..16789563); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2R:complement(16771997..16772266,16772707..16772873,16773786..16773911,16774028..16774232,16783216..16783350,16783980..16784275,16789533..16789563); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751,FlyMine:FBpp0288728,modMine:FBpp0288728; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(20902028..20902058,20896475..20896770,20895711..20895845,20886523..20886727,20886281..20886406,20885202..20885368,20884492..20884761)); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751,FlyMine:FBpp0288728,modMine:FBpp0288728; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(20902028..20902058,20896475..20896770,20895711..20895845,20886523..20886727,20886281..20886406,20885202..20885368,20884492..20884761)); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751,FlyMine:FBpp0288728,modMine:FBpp0288728; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0288728 type=protein; loc=2R:complement(join(20902028..20902058,20896475..20896770,20895711..20895845,20886523..20886727,20886281..20886406,20885202..20885368,20884492..20884761)); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751,FlyMine:FBpp0288728,modMine:FBpp0288728; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(20902028..20902058,20896475..20896770,20895711..20895845,20886523..20886727,20886281..20886406,20885202..20885368,20884492..20884761)); ID=FBpp0288728; name=otp-PE; parent=FBgn0015524,FBtr0290289; dbxref=FlyBase:FBpp0288728,FlyBase_Annotation_IDs:CG10036-PE,REFSEQ:NP_001097388,GB_protein:AAS64751,UniProt/Swiss-Prot:P56672,FlyMine:FBpp0288728,modMine:FBpp0288728; MD5=1865f3262dd7302ea5387ac5e934cae3; length=409; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 409 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    Biological Process: central nervous system development [NAS]
    regulation of transcription, DNA-dependent [IEA]
    regulation of transcription [IEA][ISS]
    segment specification [NAS]
    Molecular Function: DNA binding [IDA]
    transcription factor activity [ISS]
    specific RNA polymerase II transcription factor activity [NAS]
    sequence-specific DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNNLGANVL GPKDCDLPKA ALTALHAGVN SFGQLPVGPN LADLGGGAGG GGSSGGVPVG  60
   61 GGVARLHISG GLCDNSNALN GGNGSSGNGN GNNNNGNGNN NNSMQQQDQK RHRTRFTPAQ 120
  121 LNELERCFSK THYPDIFMRE EIAMRIGLTE SRVQVWFQNR RAKWKKRKKT TNVFRTPGAL 180
  181 LPSHGLPPFG ANITNIAMGD GLCGTGMFGG DRWSVGVNPM TAGFGQLNQS SPLSSSLNSG 240
  241 LNSGINMGSA LGAGSYQHYG LNALGDSMMY QHSVGGVSCG PSGSPSATTP PNMNSCSSVT 300
  301 PPPLSAQPNS SQNELNGEPM PLHQQQQQQT HQHQQQQTHQ HHPMAPPTPT QQQQQLPQSM 360
  361 QSPSDGANDT LHSIAALRRR ASELNAIPSY LQMAPHNYEH YNSNSNSVY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle