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Protein Overview: HIS5_THEMA

General Information:
Name(s) found: HIS5_THEMA [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Imidazole glycerol phosphate synthase subunit HisH OS=Thermotoga maritima GN=hisH PE=1 SV=1 [Swiss-Prot]
    • Organism: Thermotoga maritima
    Length: 201 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRIGIISVGP GNIMNLYRGV KRASENFEDV SIELVESPRN DLYDLLFIPG VGHFGEGMRR  60
   61 LRENDLIDFV RKHVEDERYV VGVCLGMQLL FEESEEAPGV KGLSLIEGNV VKLRSRRLPH 120
  121 MGWNEVIFKD TFPNGYYYFV HTYRAVCEEE HVLGTTEYDG EIFPSAVRKG RILGFQFHPE 180
  181 KSSKIGRKLL EKVIECSLSR R

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. HIS5_THEMA gi|122921233, gi...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..201] PSI-BLAST 32.69897 GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • imidazoleglycerol-phosphate synthase activity
    		•  2.6536917506322 bayes_pls_golite062009
  • catalytic activity
    		•  1.67435536171189 bayes_pls_golite062009
  • ligase activity
    		•  1.25010133890527 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  1.13665224189802 bayes_pls_golite062009
  • anthranilate synthase activity
    		•  0.21391494060026 bayes_pls_golite062009
  • carbon-nitrogen ligase activity, with glutamine as amido-N-donor
    		•  0.113939560975652 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.100283432019111 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle