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Protein Overview: GALE_ECOLI

General Information:
Name(s) found: GALE_ECOLI [Swiss-Prot]
Description(s) found:
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  • pir||XUECUG UDPglucose 4-epimerase (EC 5.1.3.2) - Escherichia coli (strain K-12) [NCBI NR]
  • gi|41523|emb|CAA29573.1| unnamed protein product [Escherichia coli] [NCBI NR]
  • gi|2981902|pdb|2UDP|B Chain B, Udp-Galactose 4-Epimerase Complexed With Udp-Phenol [NCBI NR]
  • gi|2981901|pdb|2UDP|A Chain A, Udp-Galactose 4-Epimerase Complexed With Udp-Phenol [NCBI NR]
  • gi|2914620|pdb|1UDC| Chain , Structure Of Udp-Galactose-4-Epimerase Complexed With Udp-Mannose [NCBI NR]
  • gi|157834065|pdb|1UDC|A Chain A, Structure Of Udp-Galactose-4-Epimerase Complexed With Udp- Mannose [NCBI NR]
  • gi|120920|sp|P09147.1|GALE_ECOLI RecName: Full=UDP-glucose 4-epimerase; AltName: Full=UDP-galactose 4-epimerase; AltName: Full=Galactowaldenase [NCBI NR]
  • UDP-glucose 4-epimerase (EC 5.1.3.2) (Galactowaldenase) (UDP-galactose 4-epimerase) - Escherichia coli [Swiss-Prot]
  • UDP-galactose 4-epimerase; UDP-galactose-4-epimerase [Escherichia coli K12]gi|1786974|gb|AAC73846.1| UDP-galactose-4-epimerase; UDP-galactose 4-epimerase [Escherichia coli K12]gi|41523|emb|CAA29573.1| unnamed protein product [Escherichia coli]gi|165134 [nrdb_11152004_Chlamydomonas]
  • UDP-glucose 4-epimerase (UDP-galactose 4-epimerase) (Galactowaldenase) [NCBI-RefSeq_human_na_08-09-2006_reversed.fasta]
  • Chain B, Udp-Galactose 4-Epimerase Complexed With Udp-Phenol [nr-271106-contam.fasta]
  • Chain A, Udp-Galactose 4-Epimerase Complexed With Udp-Phenol [nr-271106-contam.fasta]
  • Chain , Structure Of Udp-Galactose-4-Epimerase Complexed With Udp-Mannose [nr-271106-contam.fasta]
  • unnamed protein product [Escherichia coli] [nr-271106-contam.fasta]
  • UDP-glucose 4-epimerase OS=Escherichia coli (strain K12) GN=galE PE=1 SV=1 [uniprot-Ecoli-reviewed-110511.fasta]
    • Organism: Escherichia coli
    Length: 338 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR  60
   61 NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI 120
  121 FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP 180
  181 VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA 240
  241 DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW 300
  301 ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 101.0 STRUCTURE OF UDP-GALACTOSE-4-EPIMERASE COMPLEXED WITH UDP-MANNOSE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle