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Protein Overview: pde-5

General Information:
Name(s) found: pde-5 / CE40672 [WormBase]
Description(s) found:
Found 9 descriptions.
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  • WBGene00016328 locus:pde-5 cyclic nucleotide phosphodiesterase status:Partially_confirmed UniProt:P91119 protein_id:AAB53879.2 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 710 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: signal transduction [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    3',5'-cyclic-nucleotide phosphodiesterase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDASVLKYL QENPKLVEDF VVSNEISPET FKRWAVRRTM KYKNVKNGTS GGTGAWTEPD  60
   61 LSMKRRVILE TSDNRTRILY EITQCCGQLI GTNSIELIVQ NDEGAFSCRK TENGELKLKK 120
  121 VKTSKSADYI QTIVNAGNQT IAEIHFYTQL DSTEKSIVNA VCTWAAATNY YSEVRKLQKH 180
  181 ITCSFLKPKQ SFQLYTHKQE GSDGQDIHEN IAKQRKLSNF LLDVARSIFH DIVSMDAVII 240
  241 KVMNFAQKLV DADRASLFLV DSKNAQIYAR IFDVGTGDEE HVRVNSEGQK EIRFDMSKGI 300
  301 AGYVASTGEG LNIENAYEDE RFNADVDSKT GYTTKTILCM PILIRGIVIG VVQMVNKHDG 360
  361 VFTRQDEDAF EIFAVYCGLA LHHAKLYDKI RRSEQKYRVA LEVLAYHSVC NADEVNKLKK 420
  421 IEINNRIVEL ETIDFNGMRL SELEKPLYAV YMFKTLFADT LRFDTEDLIR FVLTVRKNYR 480
  481 RVAYHNWAHG WSVAHAMFAT LMNSPDAFTK LEALALYVSC LCHDLDHRGK NNAYMKTMST 540
  541 PLASIYSTSV MERHHFNQTV TILQQDGHNI LKSLSSEDYK KTLSLIKHCI LATDLALFFS 600
  601 NKAKLNVILD NNTFDINRQE HRLLTQAVMM TGCDLVASAK PWNIQTETVK VIFEEFYDQG 660
  661 DAERLSGKEP IPMMDRQQAH MLPQMQASRL HAWDLYALLR LNRANIPEKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..399] PSI-BLAST 28.69897 3',5'-cyclic nucleotide phosphodiesterase 2A, GAF A and GAF B domains
    2 View Details [400..710] PSI-BLAST 60.522879 No description for 2o8hA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle