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Protein Overview: PTFX1_ECOLI, FRY...

General Information:
Name(s) found: PTFX1_ECOLI [Swiss-Prot]
FRYA_ECOLI [Swiss-Prot]
Description(s) found:
Found 9 descriptions.
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  • Multiphosphoryl transfer protein 1 (MTP 1) [Includes: Phosphoenolpyruvate-protein phosphotransferase (EC 2.7.3.9) (Phosphotransferase system enzyme I); Phosphocarrier protein HPr (Protein H); Fructose-like phosphotransferase enzyme IIA component 2 (EC 2.7 [Swiss-Prot]
  • (P77439) Putative phosphoenolpyruvate-protein phosphotransferase fryA (EC 2.7.3.9) (Phosphotransferase system, enzyme I) [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 831 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTIQFLCPL PNGLHARPAW ELKEQCSQWQ SEITFINHRQ NAKADAKSSL ALIGTGTLFN  60
   61 DSCSLNISGS DEEQARRVLE EYIQVRFIDS DSVQPTQAEL TAHPLPRSLS RLNPDLLYGN 120
  121 VLASGVGVGT LTLLQSDSLD SYRAIPASAQ DSTRLEHSLA TLAEQLNQQL RERDGESKTI 180
  181 LSAHLSLIQD DEFAGNIRRL MTEQHQGLGA AIISNMEQVC AKLSASASDY LRERVSDIRD 240
  241 ISEQLLHITW PELKPRNKLV LEKPTILVAE DLTPSQFLSL DLKNLAGMIL EKTGRTSHTL 300
  301 ILARASAIPV LSGLPLDAIA RYAGQPAVLD AQCGVLAINP NDAVSGYYQV AQTLADKRQK 360
  361 QQAQAAAQLA YSRDNKRIDI AANIGTALEA PGAFANGAEG VGLFRTEMLY MDRDSAPDEQ 420
  421 EQFEAYQQVL LAAGDKPIIF RTMDIGGDKS IPYLNIPQEE NPFLGYRAVR IYPEFAGLFR 480
  481 TQLRAILRAA SFGNAQLMIP MVHSLDQILW VKGEIQKAIV ELKRDGLRHA ETITLGIMVE 540
  541 VPSVCYIIDH FCDEVDFFSI GSNDMTQYLY AVDRNNPRVS PLYNPITPSF LRMLQQIVTT 600
  601 AHQRGKWVGI CGELGGESRY LPLLLGLGLD ELSMSSPRIP AVKSQLRQLD SEACRELARQ 660
  661 ACECRSAQEI EALLTAFTPE EDVRPLLALE NIFVDQDFSN KEQAIQFLCG NLGVNGRTEH 720
  721 PFELEEDVWQ REEIVTTGVG FGVAIPHTKS QWIRHSSISI ARLAKPIGWQ SEMGEVELVI 780
  781 MLTLGANEGM NHVKVFSQLA RKLVNKNFRQ SLFAAQDAQS ILTLLETELT F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] PSI-BLAST 15.69897 Histidine-containing phosphocarrier protein (HPr)
    2 View Details [101..680] PSI-BLAST 168.0 No description for 2hroA was found.
    3 View Details [681..831] PSI-BLAST 28.0 Phosphotransferase IIa-mannitol

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • carbohydrate transmembrane transporter activity
    		•  4.19639384083382 bayes_pls_golite062009
  • transporter activity
    		•  2.2402957353057 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.10060320724457 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.96035963423233 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.8599676837472 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.85110072198896 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.35834547273032 bayes_pls_golite062009
  • binding
    		•  1.26946317429319 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.929895773411283 bayes_pls_golite062009
  • protein binding
    		•  0.420735403363425 bayes_pls_golite062009
  • transferase activity
    		•  0.368528690162719 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • carbohydrate transmembrane transporter activity
    		•  3.38034832098307 bayes_pls_golite062009
  • transporter activity
    		•  2.46214428476465 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.33089363600436 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.20510772344576 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.11272911420859 bayes_pls_golite062009
  • binding
    		•  1.09641102479501 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.07132012699244 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.06656635756061 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.731644896465274 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.639055128751345 bayes_pls_golite062009
  • protein binding
    		•  0.424700469684416 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  0.199622435240242 bayes_pls_golite062009
  • antiporter activity
    		•  0.00905220946391994 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.63

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle