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Protein Overview: ANAPC10

General Information:
Name(s) found: ANAPC10 [HGNC (HUGO)]
Description(s) found:
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  • gi|83026423|gb|ABB96248.1| anaphase promoting complex subunit 10 [Homo sapiens] [NCBI NR]
  • gi|6463666|dbj|BAA86953.1| APC10 [Homo sapiens] [NCBI NR]
  • gi|34395509|sp|Q9UM13.1|APC10_HUMAN RecName: Full=Anaphase-promoting complex subunit 10; Short=APC10; AltName: Full=Cyclosome subunit 10 [NCBI NR]
  • gi|150170706|ref|NP_055700.2| anaphase promoting complex subunit 10 [Homo sapiens] [NCBI NR]
  • gi|13528834|gb|AAH05217.1| ANAPC10 protein [Homo sapiens] [NCBI NR]
  • gi|119625456|gb|EAX05051.1| anaphase promoting complex subunit 10, isoform CRA_a [Homo sapiens] [NCBI NR]
  • gi|119625455|gb|EAX05050.1| anaphase promoting complex subunit 10, isoform CRA_a [Homo sapiens] [NCBI NR]
  • anaphase promoting complex subunit 10 [HGNC (HUGO)]
  • Anaphase-promoting complex subunit 10 OS=Homo sapiens GN=ANAPC10 PE=1 SV=1 [Swiss-Prot]
  • (Q9UM13) Anaphase promoting complex subunit 10 (APC10) (Cyclosome subunit 10) [Swiss-Prot]
  • ANAPC10 protein [Homo sapiens]gi|6463666|dbj|BAA86953.1| APC10 [Homo sapiens]gi|34395509|sp|Q9UM13|AP10_HUMAN Anaphase promoting complex subunit 10 (APC10) (Cyclosome subunit 10) [nrdb_11152004_Chlamydomonas]
  • Anaphase promoting complex subunit 10 (APC10) (Cyclosome subunit 10) [Yateslab_human_na_07-28-2006_reversed.fasta]
  • Tax_Id=9606 Anaphase-promoting complex subunit 10 [EBI-IPI_human_3.17_05-09-2006_con_reversed.fasta]
  • APC10 [Homo sapiens] [NCBI-RefSeq_human_na_05-03-2007_con_reversed.fasta]
  • Tax_Id=9606 Anaphase promoting complex subunit 10 [EBI-IPI_human_3.04_03-07-2005_reverse.fasta]
  • Anaphase-promoting complex subunit 10 (APC10) (Cyclosome subunit 10) [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • anaphase promoting complex subunit 10 [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • anaphase promoting complex subunit 10, isoform CRA_a [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • ANAPC10 protein [Homo sapiens] [NCBI-RefSeq_human_na_08-16-2008_con_reversed.fasta]
  • Tax_Id=9606 ANAPHASE PROMOTING COMPLEX SUBUNIT 10 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=9606 Gene_Symbol=ANAPC10 Anaphase-promoting complex subunit 10 [human-ipi-250309-contam.fasta]
  • IPI:IPI00007088.6|SWISS-PROT:Q9UM13|TREMBL:Q4W5I2|ENSEMBL:ENSP00000310071;ENSP00000403891|REFSEQ:NP_055700|H-INV:HIT000058291 Tax_Id=9606 Gene_Symbol=ANAPC10 Anaphase-promoting complex subunit 10 [ipi.HUMAN.fasta.20090807]
  • [human_BMb_040710_contam.fasta]
  • Tax_Id=9606 Gene_Symbol=ANAPC10 Anaphase-promoting complex subunit 10 ENSG00000164162 IPI00007088 [drosphohumanreversed.fasta]
  • anaphase-promoting complex subunit 10 [Homo sapiens] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Q9UM13;Q2V500;Q9UG51;Q9Y5R0; RecName: Full=Anaphase-promoting complex subunit 10; AltName: Full=Cyclosome subunit 10; [UniProt_Human_2010_06_06-01-2010_reversed.fasta]
  • Anaphase-promoting complex subunit 10 OS=Homo sapiens GN=ANAPC10 [011711_HMR.fasta]
  • IPI:IPI00007088.6|SWISS-PROT:Q9UM13|TREMBL:D3DNZ7;Q4W5I2|ENSEMBL:ENSP00000310071;ENSP00000403891|REFSEQ:NP_055700|H-INV:HIT000058291 Tax_Id=9606 Gene_Symbol=ANAPC10 Anaphase-promoting complex subunit 10 [ipi.HUMAN.fasta.20100406]
  • Anaphase-promoting complex subunit 10 n=21 Tax=Euteleostomi RepID=APC10_HUMAN [UniProt_Xenopus_laevis_01-01-2011_reversed.fasta]
  • GeneSymbol=ANAPC10 Synonyms=APC10|DKFZp564L0562|DOC1 anaphase-promoting complex subunit 10 [Homo sapiens] [NCBI-RefSeq_Human_Seno_07-12-2011_reversed.fasta]
  • IPI:IPI00007088.6|SWISS-PROT:Q9UM13|TREMBL:Q4W5I2|ENSEMBL:ENSP00000310071;ENSP00000403891;ENSP00000423995|REFSEQ:NP_055700|H-INV:HIT000058291|VEGA:OTTHUMP00000220297;OTTHUMP00000220298;OTTHUMP00000220299 Tax_Id=9606 Gene_Symbol=ANAPC10 Anaphase-promoting complex subunit 10 [ipi.HUMAN.20110912.fasta]
  • Anaphase-promoting complex subunit 10 GN=ANAPC10 [Doctor+uniprot-HUMAN-120911.fasta]
    • Organism: Homo sapiens
    Length: 185 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL ETYWQSDGSQ  60
   61 PHLVNIQFRR KTTVKTLCIY ADYKSDESYT PSKISVRVGN NFHNLQEIRQ LELVEPSGWI 120
  121 HVPLTDNHKK PTRTFMIQIA VLANHQNGRD THMRQIKIYT PVEESSIGKF PRCTTIDFMM 180
  181 YRSIR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..185] PSI-BLAST 65.39794 APC10/DOC1 subunit of the anaphase-promoting complex

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  6.427112868929 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  6.29598849092712 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  5.30907713949929 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  4.14514352069465 bayes_pls_golite062009
  • binding
    		•  2.31774167130542 bayes_pls_golite062009
  • ligase activity
    		•  2.23368019733876 bayes_pls_golite062009
  • protein binding
    		•  0.858220907931067 bayes_pls_golite062009
  • hydrolase activity
    		•  0.690426836233441 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.533285414042183 bayes_pls_golite062009
  • DNA binding
    		•  0.324772578014229 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle