Protein Overview: ABCG8_RAT

General Information:
Name(s) found:	ABCG8_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|38258880\|sp\|P58428.2\|ABCG8_RAT RecName: Full=ATP-binding cassette sub-family G member 8; AltName: Full=Sterolin-2 [NCBI NR] (P58428) ATP-binding cassette, sub-family G, member 8 (Sterolin-2) [Swiss-Prot] ATP-binding cassette sub-family G member 8 OS=Rattus norvegicus GN=Abcg8 PE=2 SV=2 [Swiss-Prot] ATP-binding cassette, sub-family G, member 8 (Sterolin-2) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 3 of ATP-binding cassette sub-family G member 8 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 3 of ATP-binding cassette, sub-family G, member 8 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] ATP-binding cassette sub-family G member 8 (Sterolin-2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 3 OF ATP-BINDING CASSETTE, SUB-FAMILY G, MEMBER 8 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Abcg8 Isoform 3 of ATP-binding cassette sub-family G member 8 [rat-ipi-250309-contam.fasta] Isoform 3 of ATP-binding cassette sub-family G member 8 OS=Rattus norvegicus GN=Abcg8 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	694 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] plasma membrane [UNKNOWN] apical plasma membrane [UNKNOWN] ATP-binding cassette (ABC) transporter complex [TAS]
Biological Process:	response to nutrient [IEP] negative regulation of intestinal cholesterol absorption [UNKNOWN] transport [IEA] cholesterol homeostasis [UNKNOWN] excretion [UNKNOWN] sterol homeostasis [UNKNOWN] negative regulation of intestinal phytosterol absorption [UNKNOWN] sterol transport [UNKNOWN][TAS] response to drug [IEP] phospholipid transport [UNKNOWN] cholesterol efflux [UNKNOWN] cholesterol transport [TAS] regulation of intestinal cholesterol absorption [TAS]
Molecular Function:	nucleotide binding [IEA] ATPase activity [UNKNOWN][IEA] ATP binding [UNKNOWN][IEA] protein heterodimerization activity [UNKNOWN] cholesterol transporter activity [UNKNOWN][TAS] sterol transporter activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEKTKEETQ LWNGTVLQDA SSLQDSVFSS ESDNSLYFTY SGQSNTLEVR DLTYQGGTCL  60
   61 RSWGQEDPHM SLGLSESVDM ASQVPWFEQL AQFKLPWRSR GSQDSWDLGI RNLSFKVRSG 120
  121 QMLAIIGSAG CGRATLLDVI TGRDHGGKMK SGQIWINGQP STPQLIQKCV AHVRQQDQLL 180
  181 PNLTVRETLT FIAQMRLPKT FSQAQRDKRV EDVIAELRLR QCANTRVGNT YVRGVSGGER 240
  241 RRVSIGVQLL WNPGILILDE PTSGLDSFTA HNLVRTLSRL AKGNRLVLIS LHQPRSDIFR 300
  301 LFDLVLLMTS GTPIYLGVAQ HMVQYFTSIG YPCPRYSNPA DFYVDLTSID RRSKEQEVAT 360
  361 MEKARLLAAL FLEKVQGFDD FLWKAEAKSL DTGTYAVSQT LTQDTNCGTA AELPGMIQQF 420
  421 TTLIRRQISN DFRDLPTLFI HGAEACLMSL IIGFLYYGHA DKPLSFMDMA ALLFMIGALI 480
  481 PFNVILDVVS KCHSERSLLY YELEDGLYTA GPYFFAKVLG ELPEHCAYVI IYGMPIYWLT 540
  541 NLRPGPELFL LHFMLLWLVV FCCRTMALAA SAMLPTFHMS SFCCNALYNS FYLTAGFMIN 600
  601 LNNLWIVPAW ISKMSFLRWC FSGLMQIQFN GHIYTTQIGN LTFSVPGDAM VTAMDLNSHP 660
  661 LYAIYLIVIG ISCGFLSLYY LSLKFIKQKS IQDW

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ABCG8_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: