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Protein Overview: vab-10

General Information:
Name(s) found: vab-10 / CE36463 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00006876 locus:vab-10 status:Partially_confirmed UniProt:G5ECG5 protein_id:CAH04743.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 4410 amino acids

    Gene Ontology:
    Cellular Component: intracellular organelle [IDALink to PubMed article]
    basal plasma membrane [IDALink to PubMed article]
    membrane [IEALink to PubMed article]
    intermediate filament [IDALink to PubMed article]
    apical plasma membrane [IDALink to PubMed article]
    proteinaceous extracellular matrix [IEALink to PubMed article]
    Biological Process: cell cycle arrest [IEALink to PubMed article]
    DNA repair [IEALink to PubMed article]
    hermaphrodite genitalia development [IMPLink to PubMed article]
    signal transduction [IEALink to PubMed article]
    locomotion [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    post-embryonic body morphogenesis [IMPLink to PubMed articleLink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed article]
    protein amino acid dephosphorylation [IEALink to PubMed article]
    cell adhesion [IEALink to PubMed article]
    gamete generation [IMPLink to PubMed article]
    blood coagulation [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    growth [IMPLink to PubMed article]
    chemotaxis [IEALink to PubMed article]
    locomotory behavior [IMPLink to PubMed articleLink to PubMed article]
    nematode larval development [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    morphogenesis of an epithelium [IMPLink to PubMed article]
    gastrulation with mouth forming first [IMPLink to PubMed article]
    Molecular Function: actin binding [IEALink to PubMed article]
    protein tyrosine phosphatase activity [IEALink to PubMed article]
    calcium ion binding [IEALink to PubMed article]
    signal transducer activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGERYRSHH AVDPSDAQEK EVLDHYELNR EKYNDERDNV QKKTFTKWVN KHLSKTDHKI  60
   61 DDLFVDLRDG YALIALLEAL TGERIQKENG YTRFHRIQNV QYCLDFLKKK NIKLVNIRPE 120
  121 DIVEGNGKLT LGLIWTIILN FQVSVIRQRL LLESSQHEQM SAKHTTTNSQ VSLHGSDATS 180
  181 ARDALLQWAR RVTAGYPRVN VNNFSSSWRD GLAFNAILHR YRSSAIDWNK ISSDSVSNTE 240
  241 RLNNAFAAAD REFGVERLLD AEDVDTNNPD EKSIITYVSS LYNALPHEPE MSRLQKVQEE 300
  301 YIEEAYEWRE WVVRAIQLVD DRHLQGTASE LIYELQRFRE DDLPPREEQK RRLTLVYEHL 360
  361 EKVMRSTELF AIPHELSAPE LQRVWNELQN SIDRRFDVLE RHRIQEGNSN DLLSRLARGI 420
  421 GITNEKLDLI LKRIEDVEAR VDTSPPAAVE RTVSEIVDDL NALESPIARF FEDVEELKSM 480
  481 QHPEANDFYK QVYGLHQRRT TYLDRLTNQI LVRLGVRTDS LHKENQQRLE NMRKTSFSRV 540
  541 EECIEWVRVR MEKLTTMEFL EDLETLEHVF EQHKFDNRDI QDFRQNVDEC IARQAEVSAE 600
  601 DTYEYCELLR VLESEYQQLR DLSAGRMLDL DSLIAFVRAA QLELIWVSER ESIEVTRNWS 660
  661 DIKQLDLPML TNYYKQLLHE MELREKQYND VHNQGAALLN QGHPAIRVIE VYLRQMQSQW 720
  721 DWLLALSKCL EEHLRDALNL KSFMEEASDA EAWIQEQSVR LENNYNRTDF SLEEGERFLR 780
  781 ELDEIKEILN KYHQVLMALT ERCASISPLW QRGERIPHPI KVTALCDYSD ENVTIKAGDD 840
  841 VYLLDNSDLI KWTIRDISGA EGQVPSVVFR IPPTDARLTA LLNRLLQQFE KLKKLWDKKH 900
  901 RMVRFNMVLN TMRTIQGWDL DTFNSIDPDQ RDAIMKALND DANKLLSELD PNDPLALRLR 960
  961 EELRRTNEHF WNLLNASQKP PEPDWASQYD QKMAELLKKL EEAWRELNDA VGKPISRSPE1020
 1021 DLERVIHAHK RFEDALQALD SDVANVKELF RQLPNPTPTQ RVNHDRLNGL WDDLWDLSRM1080
 1081 YVERIKVLES VLNGMVEVAD IVRQHEITLN SFDDLPAALD KLRGHHSQLL EINMVLKVSK1140
 1141 LGAQNEHFSQ QQTVIDQLNR NVALLRQHVS RTRINEGHHP DVDAIEDEVQ KLNVRWENVN1200
 1201 SQIASRLLAV ESALQIQMVY RSEYETEMSW LDTVEETINR LRKPEELRPE QYQQQLDMLI1260
 1261 AEYTNLQEHT QAIEHVNKEG GRFIHEAKIF DAKLGQYSDG IVGIHGPGIK SEFRRTKPQP1320
 1321 KNGSQIVTEE LELLNRRFAQ LSSLILERRN TMQVLIQNWK RQKQENVTQV VSFREAEVSG1380
 1381 MMTDLTRFRQ EIFTTHLTFN SNPESIDAAT KNVQNVKQSL DSWRDRIKER LDEIDRLCTE1440
 1441 EGDSLTPEQY SALREMRRQL ADEYDTVLRT VEGIHTRLNI LSALLIEFSS VTSSMQSWMT1500
 1501 DRTRLAGDIR HKSGDPMRID EARFEAKSLM DEVIREESRL KTIGASVLKI EQEISAMRDD1560
 1561 VRASGSTDDV GISVDEVYET RRRVEDDYMQ LLRQCQDLIS FQNRLHAMND EHSEQARRAD1620
 1621 EWLQMLQNDV EDVDQDPRFQ RDEDRIQRIE ELNRMAAGGS SQLDDAEQAS RRLLTALEGT1680
 1681 NVANDVRARH EELANLRRGK HQKVIDRLSQ NMMEAASRKA EAEGVKQAVE NLRQWSEQTA1740
 1741 QRTRQPVQLP LTELDLHEAR KDEQVLHGEI ENRLALIEEL EKKAADVGDH ASLAELQECK1800
 1801 MKLKRSNSDL KGLRDNIFDA INGLQTVNSE GETLSRAVDS AGAKIRSARL PEAQSEVEAL1860
 1861 QDQADNLERI TNNLCNIPNV TRTEPVIQKS KDLRKRVDSC AQELDARMGK LAELESLDAE1920
 1921 FDGAKNKLSS FIGAFDDELK GLEKVSIDKE KLAEQRRQTQ DLVDKHSEGN AILDDVEAIA1980
 1981 QKVTAEDPSK TGSAQKSVGE LGARLQRQAS ELKARGDKIN KLDSKATSFA ESEAAVLGYI2040
 2041 EKQKDQLSTG FPVPATKEGV KSQLLDLERM NKTGKEEQRR VDDARHSARE LAREASVEKE2100
 2101 VQDMNQREKK LLDEWEDLAD QFDASESQKA AGKINSLVAE IADLDPIGRS RDELQKQKKE2160
 2161 VVELAGDLGS AQTKMLELGA EWEAALGAGI VAQPVFEMNR AATDELNKLA ARAGKRLAQR2220
 2221 EKKITETEDE IDKLHADADQ IVGALEAIAK DEALQGAPSQ LLDPKQVSEK VRQLKESLKP2280
 2281 VGEKMDAFNT DCKLLIKTAG PESDTKELDS LLKKVGDAYS DVVGKVSDKE MSVDAAVQQQ2340
 2341 GKVEDAYRAL LNWLEETEEM MENRKKPSAD AKVAKAQLHD YEVLMKHVED KKPSVDGFKA2400
 2401 MIEKIVAEAS SDEEKKALGN KNAQIEDRYK DLLNSAVDRQ RKLLDAVDLA ERLQEVTIPL2460
 2461 DSWLQSADKR LQALAKVPIT VEKAEEMIGE QEALQDELEH KSDDLKDVLE IAPMLASLVS2520
 2521 VEDANSISGQ VNQLEARARA LDAGITNMRP LLESFLQQIQ DFTLDAEDMT QFVGETEVKL2580
 2581 GELDELPIEP DDLVEQTNIL AEIAVSIADR DEMMANIFEV GKQLAIQGEP EEALIAQKKL2640
 2641 DDLKFRYADL MTSADEKIAL LAKAIPLSEG FHEGFDTVMQ VLEDMDRDLQ TIDEEDPETQ2700
 2701 AELIFLLEED ISQKMRPSVD ELTALSNQLQ VLCSADKADE LQTNTIAMNK LVNSVADRVA2760
 2761 RRAERIEMAS KQSRAVLDDL QYLIEWFSAA RERILEGAPP SLDLEVLKSQ LKHQRITNEE2820
 2821 ASANKVQFRN VAGEAKKVAR QLGMEGNEAN EKISDTVDEG KELVEEVMAL CADRTETLER2880
 2881 ALALMEQLTS QFDELNKWLD QMDAELQASP SVTTATPAAE LREMHDHNEE LARMVAAYRP2940
 2941 IIEGFKSDVG SLHEVLAEDQ APLLESVAGE LVQGYEEVRE AVRARGHAID NMMGATIGFG3000
 3001 ERLETLVANL QGAADRLREN EGISADPSVL ESRLAENRSI VESLRDKQNA YDALKQTASE3060
 3061 LLASAPEGDA AAGDVENKLN RLEKLWKEIE REAVDRGVLL EDVLDKAKHF WSELDSCQKA3120
 3121 VDDLRNRLEL VEPATGHPEQ LADQQEIMAQ VASEMERARP RIEALSIAGK QLADYVPDDE3180
 3181 KAVIENQVAN VRGGFSTITG LFAEKKRDLI AAMEEAMTFH GDLQELLKWL DMAEQKLLKM3240
 3241 SPVEHAKHMT EIEQLLKELH TFKDEVHERG VAKEQVVATA LQLAADAPPH LAATVRQPVA3300
 3301 DLNTRWSRLN AALAEREHKL ENLMLQMGKL ASTIAQLTAW MDKTRATLKD IAPPKNAVNL3360
 3361 RDIEIAQCKL VVLSNDIHAH QDSVNAVNRA AQKYIQTSGA LDAETSDSLK SMNLKWEDIQ3420
 3421 KVLESLAFDM EVAKKEAENV GGEVEKWQRW LEETESALLS TKPTGGLPET AEFQLDEFKA3480
 3481 LKLDVEHNAS PLEAHLHATE QHLKEEPQDA DTWLSKTHGA MKTKWNKVKE LLVDREKKLQ3540
 3541 VAYEQAVALE SALNDMEDWI IAAERKLTDQ PSISRLPDVI EKQLAEHESW MEEVAGRKMA3600
 3601 MTKHQASGVH MQYYCEKKDA IPIKNRLVSL KHRVEKISGR TAERAKQLAV TRDEVATWQD3660
 3661 GLHDLEHFIS DVLVKIAPEP NTTSSLEKLK AKLEEVKEAQ RDVTAKQTLF DVTRKRGIGL3720
 3721 AERATRSEYK QISMTNEKMS KKWAEMLKKL RDRLREAEQA VLEGGAFEES MNDLESWVDD3780
 3781 ELERYQKAEH EPVFADIDGV RALVDEESRR SAERKTKENG VKTVVKKADA LMASGVDEKD3840
 3841 SIAQAKERLV EKWNQVEEAA RHRGNSIKEA EQAAEEFDAK THALLDWLAV EEQKLKASGL3900
 3901 DEVEGVKQEM DEAKGRYQEC LKKGEEILSK CQPAAEPILR NWMRVVEARW KEVSEKVDER3960
 3961 EFTLLEQEQK AKEQNEQIEK LAKFAAQKRE ELNRMIEQPP AQDLDTMEQN ICDFANLDSE4020
 4021 LREQQPEVDA ACKSAKKGAR NPAAEMLSTE WKKLWLDAMG LQSSLDNQKA LLEEMKRLEG4080
 4081 WKWEDWKERY VEWNDHAKAR VNDLFRRIDR LHTGNVPRQV FIDGIIGSNY VPNSTIVYSK4140
 4141 FPTSRLEMAK VADRFDKGDG MINAKEFINA LRFDASNRNA KPQTDTEKIT HEIELQKKTC4200
 4201 SCCTPYQIEK ISENHYRFGD THIKRMVRIL RSTVMVRVGG GWESLDEFLH KHDPCRAKGR4260
 4261 LNINMFPEAR PIHALDSMRS FTKNRHGKQL PTTGTPGPIM KIREKTDRSV PMSGGLGGTA4320
 4321 GYTVTTDSHR HTDARPSRIP RAPSDMSAGR LSRVGSVSNS KNSIVDSSTP SRPESRASSD4380
 4381 AGDRQTRIPS LRARKGQRYI PQGPSSSSSK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run hcp-2 hcp2 ip from december Cheeseman, I.M., et al. (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle