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Protein Overview: CE37296

General Information:
Name(s) found: CE37296 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00022199 locus:pfk-1 status:Confirmed UniProt:Q95X24 protein_id:CCD71596.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 578 amino acids

    Gene Ontology:
    Cellular Component: 6-phosphofructokinase complex [IEALink to PubMed article]
    cytoplasm [IEALink to PubMed article]
    Biological Process: embryonic development ending in birth or egg hatching [IMPLink to PubMed articleLink to PubMed article]
    glycolysis [IEALink to PubMed article]
    fructose 6-phosphate metabolic process [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    phosphofructokinase activity [IEALink to PubMed article]
    6-phosphofructokinase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIGTDSALQ RIISSIDAVV ATAQSHQRAF VIEVMGRHCG YLALVAALAS EADFCFIPEW  60
   61 PAPENWRDVL CDKLSQMRSE GQRLNIIIVA EGAIDRDGKA ITAEDVKTAV KEKLKYDTRV 120
  121 TILGHVQRGG APSAFDRLLG CRMGAEAVFA LMEMTEESEP CVISIDGNVM VRVPLLKCVE 180
  181 RTQMVQKAMA DKDWTTAVML RGRSFQRNLE TYKLLTKMRT VEKDNLSEGH KFNVAVINVG 240
  241 APAGGMNAAV RSYVRMALYH QCTVYGIEDS FEGLANGSFK QFKWSDVTNW AMNGGSFLGT 300
  301 QKSLPTEKTM PQLAAQLKKH NIQALLLVGG FEAYHSTIIL AENREKYPEF CIPMCVIPCT 360
  361 ISNNVPGTMV SLGSDTAINE ICQMIDKIKQ SATGTKRRVF IVETMGGYCG YLATLSALSS 420
  421 GADNAYIFEE PFTVQDLSDD VDVILSKMEV GAKRYLVVRN EWADKNLTTD FVQNLFDSEG 480
  481 KKNFTTRVNV LGHVQQGGSP TPFDRNMGTK LAARALEFLL IQLKENLTAD NKVIAKSAHT 540
  541 ATLLGLKGRK VVFTPVQDLK KETDFEHRLP SEQWLVDK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] FFAS03 5.37 The crystal structure of phosphofructokinase from Lactobacillus delbrueckii
    2 View Details [230..578] PSI-BLAST 97.0 ATP-dependent phosphofructokinase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • 6-phosphofructokinase activity
    		•  12.7403693686468 bayes_pls_golite062009
  • phosphofructokinase activity
    		•  11.7059647240147 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  9.54757838113048 bayes_pls_golite062009
  • fructose-6-phosphate binding
    		•  7.12870468168491 bayes_pls_golite062009
  • fructose binding
    		•  7.0070117394116 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.40595318732289 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.20407391743017 bayes_pls_golite062009
  • kinase activity
    		•  2.09076306615481 bayes_pls_golite062009
  • transferase activity
    		•  1.97789134877808 bayes_pls_golite062009
  • catalytic activity
    		•  1.89212073381079 bayes_pls_golite062009
  • monosaccharide binding
    		•  0.93954836516667 bayes_pls_golite062009
  • binding
    		•  0.692710585652872 bayes_pls_golite062009
  • hydrolase activity
    		•  0.276140444059183 bayes_pls_golite062009
  • fructose-2,6-bisphosphate 2-phosphatase activity
    		•  0.13423626204854 bayes_pls_golite062009
  • sugar binding
    		•  0.0026978348896064 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.88

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle