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Protein Overview: exp-1

General Information:
Name(s) found: exp-1 / CE37026 [WormBase]
Description(s) found:
Found 17 descriptions.
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  • WBGene00001373 locus:exp-1 Gamma-aminobutyric acid receptor exp-1 status:Partially_confirmed UniProt:G5ECJ0 protein_id:CCD70946.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 539 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    neuromuscular junction [IDALink to PubMed article]
    Biological Process: potassium ion transport [IDALink to PubMed article]
    sodium ion transport [IDALink to PubMed article]
    ion transport [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    positive regulation of muscle contraction [IMPLink to PubMed article]
    defecation [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: GABA receptor activity [IDALink to PubMed article]
    excitatory extracellular ligand-gated ion channel activity [IDALink to PubMed article]
    neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASILILAT CHQVLADFNS YVVPQPHAQR DHRQDISQHY DYLMEENDEP LGRGAAPSKY  60
   61 RSSHGQAQHR PEMTESENFA QPNTESVFSS GGVDSYGETR DFLQFLRRIQ YDHRQVPENE 120
  121 KGEATYVEVS VVVSNIRAVS EVTMDYALEL FYRESWRDPR LQYDRKLFKN KTELALHESY 180
  181 TNFLWFPDTF VPNAIASKNP QRNSISHRSL LRLDETGKLL YSRRISLVCE CTMDLTLFPF 240
  241 DKQLCKLGIE SYGYTADHVV YKWSKGARTA LELKKIRLPD FTIQEAYVTS QMESYATGNY 300
  301 SRLYVCFVFS RSSGFCFLQL IIPSTAVVIT SWVSLWMETE TEFQDMISII LAITFLIFSY 360
  361 NEMMPRVSYI KAMDIYLGVC FMIVFLSLIK LALVKYMRQK IMLTSDSGNS LREMSQMSTR 420
  421 QRLRARKTSN MNFRNNGGGS IPINEEHQQM LTVPNGEDKM ANGDDKEANN NGKSHLSDML 480
  481 EIRITQRTMH RFHWISQMLF FFGFVIFCLF YFLIYPNLHI VSVDPACDKN LAEWFADIY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] MSA 1.209993 View MSA. No confident structure predictions are available.
    2 View Details [89..401] PSI-BLAST 72.0 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    3 View Details [402..539] PSI-BLAST 29.09691 Acetylcholine receptor protein, alpha chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle