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View Structure Prediction Details

Protein: exp-1
Organism: Caenorhabditis elegans
Length: 539 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for exp-1.

Description E-value Query
Range
Subject
Range
gi|37626089 - gi|37626089|gb|AAQ96594.1| excitatory GABA receptor EXP-1A [Caenorhabditis elegans]
412.0 [0..1] [539..1]

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Predicted Domain #1
Region A:
Residues: [1-88]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASILILAT CHQVLADFNS YVVPQPHAQR DHRQDISQHY DYLMEENDEP LGRGAAPSKY  60
   61 RSSHGQAQHR PEMTESENFA QPNTESVF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [89-401]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSGGVDSYGE TRDFLQFLRR IQYDHRQVPE NEKGEATYVE VSVVVSNIRA VSEVTMDYAL  60
   61 ELFYRESWRD PRLQYDRKLF KNKTELALHE SYTNFLWFPD TFVPNAIASK NPQRNSISHR 120
  121 SLLRLDETGK LLYSRRISLV CECTMDLTLF PFDKQLCKLG IESYGYTADH VVYKWSKGAR 180
  181 TALELKKIRL PDFTIQEAYV TSQMESYATG NYSRLYVCFV FSRSSGFCFL QLIIPSTAVV 240
  241 ITSWVSLWME TETEFQDMIS IILAITFLIF SYNEMMPRVS YIKAMDIYLG VCFMIVFLSL 300
  301 IKLALVKYMR QKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.0
Match: 2bg9A
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [402-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTSDSGNSL REMSQMSTRQ RLRARKTSNM NFRNNGGGSI PINEEHQQML TVPNGEDKMA  60
   61 NGDDKEANNN GKSHLSDMLE IRITQRTMHR FHWISQMLFF FGFVIFCLFY FLIYPNLHIV 120
  121 SVDPACDKNL AEWFADIY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 29.09691
Match: 1oedA
Description: Acetylcholine receptor protein, alpha chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle