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Protein Overview: acr-23

General Information:
Name(s) found: acr-23 / CE36939 [WormBase]
Description(s) found:
Found 18 descriptions.
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  • WBGene00000062 locus:acr-23 status:Confirmed UniProt:G5EG88 protein_id:CCD72123.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 545 amino acids

    Gene Ontology:
    Cellular Component: postsynaptic membrane [IEALink to PubMed article]
    membrane [IEALink to PubMed article]
    integral to membrane [IEALink to PubMed article]
    synapse [ICLink to PubMed article]
    Biological Process: ion transport [IEALink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    synaptic transmission [IMPLink to PubMed article]
    transport [IEALink to PubMed article]
    Molecular Function: acetylcholine receptor activity [ISSLink to PubMed article]
    neurotransmitter receptor activity [IEALink to PubMed article]
    extracellular ligand-gated ion channel activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHRIYTFLIF ISQLALGLSN NPDIPIQYEL ANNIMENYQK GLIPKVRKGS PINVTLSLQL  60
   61 YQIIQVNEPQ QYLLLNAWAV ERWVDQMLGW DPSEFDNETE IMARHDDIWL PDTTLYNSLE 120
  121 MDDSASKKLT HVKLTTLGKN QGAMVELLYP TIYKISCLLN LKYFPFDTQT CRMTFGSWSF 180
  181 DNSLIDYFPR TFTNGPIGLA NFLENDAWSV LGTKVNREEK KYTCCPVNYT LLHYDVVIQR 240
  241 KPLYYVLNLI APTAVITFIS IIGFFTSVNP FTNFCNVSSS VHDLRQEKIT LGITTLLSMS 300
  301 IMIFMVSDKM PSTSTCVPLI ALFYTLMITI ISVGTLAASS VIFVQKLGSI GNPPASKTMK 360
  361 WTHRIAPFVL IQMPLVMKQA YAKRAKEEKH RKRMSRKNSM WTKVYHLARD HSKLMETVPD 420
  421 GAVKFNQISD FKNNDIGNME SPRMAESQTS ETFAAPMDTS FTESLHIPEL NRVASSNSIQ 480
  481 SVLKPTEIQL TPYCTRNIVE LEWDWVAAVL ERVFLIFFTI CFLFSAIGIN LYGWYIWYTE 540
  541 NHFLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..374] PSI-BLAST 71.69897 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
    2 View Details [375..545] PSI-BLAST 39.30103 Acetylcholine receptor protein, gamma chain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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