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Protein Overview: egl-8

General Information:
Name(s) found: egl-8 / CE36909 [WormBase]
Description(s) found:
Found 16 descriptions.
SHOW ALL
  • WBGene00001177 locus:egl-8 status:Confirmed UniProt:Q6EZG7 protein_id:CCD61784.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 592 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of pharyngeal pumping [IGILink to PubMed article][IMPLink to PubMed article]
    regulation of oviposition [IMPLink to PubMed article]
    regulation of locomotion [IGILink to PubMed article]
    signal transduction [IEALink to PubMed article]
    positive regulation of growth rate [IMPLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    lipid metabolic process [IEALink to PubMed article]
    dopamine receptor signaling pathway [IMPLink to PubMed article]
    positive regulation of locomotion [IMPLink to PubMed article]
    Molecular Function: phosphoinositide phospholipase C activity [IEALink to PubMed article]
    phospholipase C activity [IEALink to PubMed article]
    calcium ion binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKEFQFNWK PTIIPELLHG SVFDRYDDES TCLELNAQVR IDENGFFLRW LIEGKDAVVL  60
   61 DMGQIWEART GGLPKDGRIM FELEQRGASE TIAERTIWIT HGQDLVNVQS FFLVAESVEL 120
  121 AKTCRAGIND ILKSSRIRHV CPTTQLMKYH TWLTMNVNER RKIPIKLIIK TFSSGKPEKM 180
  181 VQKCLNDLGL GGDKYTPARV INRSMGKKFR NFYKCSRGRK RKEREELDVD ILTFEKFQRL 240
  241 YNKICPRTEV QELFVKLSGQ KEYLTKERLI NFLNEEQRDP RLNEILFPFF DSQRIVALLK 300
  301 KHENDIKYQE DGKMSGDGFL RFLMSDENPP VFLDRIEMFM DMDQPLCHYY INSSHNTYLT 360
  361 GRQYGGKSSS EIYRQVLLSG CRCIELDCWD GTGENKGEPI ITHGKAMCTD VFFKDVLVQI 420
  421 RDTAFARSDF PVVLSFENHC SKSNQLKMAK YCMDIFGDML LSKPFEDAPL DPGVSLPSPN 480
  481 RLRKKILIKN KRLKTDIERH QLDQFLREGK LDEEDELNET PEVVGEDSVS PREMPAKEND 540
  541 EAHPELKQNF IAKNLKGFGF SKKQETNKIS NFNIVFKGFL FLLILILLSQ IP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..592] PSI-BLAST 141.0 No description for 2fjuB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.597587183571285 bayes_pls_golite062009
  • protein binding
    		•  0.29116370406325 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.05056572092175 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.0304825793447705 bayes_pls_golite062009
  • phosphoric diester hydrolase activity
    		•  0.01534375493934 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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