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Protein Overview: crm-1

General Information:
Name(s) found: crm-1 / CE36907 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00007103 locus:crm-1 status:Confirmed UniProt:G5EDX8 protein_id:CAH04640.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 671 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEALink to PubMed article]
    Biological Process: regulation of cell growth [IEALink to PubMed article]
    reproduction [IMPLink to PubMed article]
    Molecular Function: serine-type endopeptidase inhibitor activity [IEALink to PubMed article]
    insulin-like growth factor binding [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQLVVCVFLL LFSFVNFLRT EQSERMHDDC LKAICPLVFH KGCPSDSQLI TVSPAPGNCC  60
   61 PPPGSCHCDQ KKCVPSVPTC TKEERLVMVE KGSDIPGKCC AYYECHKKEK KCENVHCPPM 120
  121 FQDEEECPPD SIRPPESISK ESCCPIRQSC KCRGSICRPA QCPDGKVVNV TKKGTGFPGR 180
  181 CCDKWECVDA ELSKAKCNHS GIERQPLETW HVSDCESCQC IRGVSVCNKM TCPKVNQECT 240
  241 WIGIPTGECC PVCLGCQTDN QTKLERGATW QKDDCTSCTC SELGAHMCEK YMCKTDCENP 300
  301 RKVEGQCCPV CDEPTIIRPP ATCPSLELCS LRCANGLRRD NIGCYVCECL PDEVPTNPRC 360
  361 RELNDENCEK QCAHGYLKDE DGCTVCKCSK CPPLHQCHKH CLYGFETNSA GCSLCKCRAS 420
  421 SKLDKKQGTT KSTKLGAGSA QQTEYHSEKC ISFSNDGHQI VRDGGEWWSD GCRHCFCENK 480
  481 QEFCSLISCP TKPSDCADEK WVQKEDECCP SCIDQKKKPK SSNSLAAQKH EHTVCQSPGT 540
  541 GRLFTDGETW QLAPCVSCTC RVGHVLCRTT ECPPIACPNP EYQNEEDCCP TCPEQKVENT 600
  601 KNEKGDTIVC TDDAGTAHIV AAQVQRSRPN SIGGSINSKT FSVKNNWIHA KTRGLEGHER 660
  661 RKYGGIVEDI N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..106] deduced N/A No confident structure predictions are available.
    2 View Details [107..232] PSI-BLAST 8.221849 NMR structure of the human NOTCH-1 ligand binding region
    3 View Details [233..568] PSI-BLAST 7.69897 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    4 View Details [569..671] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.286076792172079 bayes_pls_golite062009
  • protein binding
    		•  0.14494900666454 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle