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Protein Overview: RTF1

General Information:
Name(s) found: RTF1 / YGL244W [SGD]
Description(s) found:
Found 8 descriptions.
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  • Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 458 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    transcription elongation factor complex [IPILink to PubMed article]
    Cdc73/Paf1 complex [IPILink to PubMed article][TASLink to PubMed article]
    Biological Process: histone methylation [IMPLink to PubMed article]
    telomere maintenance [IMPLink to PubMed articleLink to PubMed article]
    transcription from RNA polymerase II promoter [IMPLink to PubMed article]
    RNA elongation from RNA polymerase II promoter [IPILink to PubMed article]
    Molecular Function: RNA polymerase II transcription elongation factor activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MERETLLFER SQIMQKYQER KLFRARGRDM KEQQQRAKND EDSRKTRAST RSTHATGHSD  60
   61 IKASKLSQLK KQRARKNRHY SDNEDEDDEE DYREEDYKDD EGSEYGDDEE YNPFDRRDTY 120
  121 DKREEVEWAE EEDEQDREPE ISDFNKLRIG RSFVAKFCFY PGFEDAVKGC YGRVNVGTDK 180
  181 RTGKTSYRMV RIERVFLQKP YNMGKFYTNQ YFGVTQGKDR KVFQMNYFSD GLFAEDEYQR 240
  241 YLRALDNSQM IKPSLHSLSN KTKEVMDFVN TPLTDKTTDE VVRHRMQFNK KLSGTNAVLE 300
  301 KTVLREKLQY AKETNNEKDI AKYSAQLRNF EKRMSVYEKH HENDQSDIKK LGELTSKNRK 360
  361 LNMSNIRNAE HVKKEDSNNF DSKSDPFSRL KTRTKVYYQE IQKEENAKAK EIAQQEKLQE 420
  421 DKDAKDKREK ELLVAQFRRL GGLERMVGEL DIKFDLKF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle