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Protein Overview: STP22

General Information:
Name(s) found: STP22 / YCL008C [SGD]
Description(s) found:
  • Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 119 amino acids

    Gene Ontology:
    Cellular Component: endosome [IDALink to PubMed article][IPILink to PubMed article]
    ESCRT I complex [IDALink to PubMed article][IPILink to PubMed article]
    Biological Process: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [ICLink to PubMed article]
    telomere maintenance [IMPLink to PubMed articleLink to PubMed article]
    protein targeting to membrane [IMPLink to PubMed article][IPILink to PubMed article]
    protein targeting to vacuole [IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWVPSMYPVK PPFISINLEN FDMNTISSSL PIQEYIDSNG WIALPILHCW DPAAMNLIMV  60
   61 VQELMSLLHE PPQDQAPSLP PKPNTQLQQE GEYSPTAPKA QVSTPKTAIA STSTTSTGI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle