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Protein Overview: IRE1A_ARATH

General Information:
Name(s) found: IRE1A_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • Serine/threonine-protein kinase/endoribonuclease IRE1a OS=Arabidopsis thaliana GN=IRE1A PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 841 amino acids

    Gene Ontology:
    Cellular Component: extrinsic to endoplasmic reticulum membrane [IDA]
    Biological Process: activation of signaling protein activity involved in unfolded protein response [IMP]
    Molecular Function: kinase activity [ISS]
    endoribonuclease activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPPRCPFLRH LFFLLLLLSP WIMSPCGGAA DDVTYPIVPS SPGRRSILQI RREPPTEPNT  60
   61 KLVVDRDGKV FLKQQPKETP YWSFSTGSPM HSLYQAPANN NTENATEITR PHIIVEYLNN 120
  121 SKAATTVDGY HNWTVQEFFR QKPLVTDDGV TLGSETTSAY LVDGRSGRLI HVYKSTGDTK 180
  181 ITNALVKPAS TEDFVNEPLL IRRTDSKLEH FSKTTGKLVW NLTVSHFRAA LLCDPVFNSG 240
  241 YDLGPKLQTG IYMPLLCGSQ IDVRGPEIVI RVLHDQPMNV KMLPSPSLNH FESENSIMPF 300
  301 GKARESRKLQ EQHKQKYTYL FGQWSPVKLL APLVLLGVVV SVFIKKFSSR GSDVSLKAGP 360
  361 SKKKKNRKSA KDTNRQSVPR GQDQFELIEG GQMLLGFNNF QSGATDGRKI GKLFLSSKEI 420
  421 AKGSNGTVVF EGIYEGRPVA VKRLVRSHHE VAFKEIQNLI ASDQHTNIIR WYGVEYDQDF 480
  481 VYLSLERCTC SLDDLIKSYL EFSMTKVLEN NDSTEGVAAY KIQLDSLEGV IKGNNFWKVG 540
  541 GHPSPLMLKL MRDIVCGIVH LHELGIVHRD LKPQNVLISK DMTLSAKLSD MGISKRMSRD 600
  601 MSSLGHLATG SGSSGWQAPE QLLQGRQTRA VDMFSLGCVI FYTITGCKHP FGDDLERDVN 660
  661 IVKNKVDLFL VEHVPEASDL ISRLLNPDPD LRPSATEVLL HPMFWNSEMR LSFLRDASDR 720
  721 VELENREADS EILKAMESTA PVAIGGKWDE KLEPVFITNI GRYRRYKYDS IRDLLRVIRN 780
  781 KLNHHRELPP EIQELVGTVP EGFDEYFAVR FPKLLIEVYR VISLHCREEE VFRKYFKCDI 840
  841 I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..258] PSI-BLAST 17.0 No description for 2hz6A was found.
    2 View Details [259..707] PSI-BLAST 51.39794 Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
    3 View Details [708..841] PSI-BLAST 55.221849 No description for 2rioA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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