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Protein Overview: ICDHX_ARATH

General Information:
Name(s) found: ICDHX_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|4585978|gb|AAD25614.1|AC005287_16 NADP specific isocitrate dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • pir||A96585 NADP specific isocitrate dehydrogenase [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|15221788|ref|NP_175836.1| ICDH (ISOCITRATE DEHYDROGENASE); isocitrate dehydrogenase (NADP+)/ oxidoreductase, acting on the CH-OH group of donors, NAD or NADP as acceptor [Arabidopsis thaliana] [NCBI NR]
  • gi|12744346|gb|AAK06592.1|AF316501_1 NADP-specific isocitrate dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|109134149|gb|ABG25072.1| At1g54340 [Arabidopsis thaliana] [NCBI NR]
  • Peroxisomal isocitrate dehydrogenase [NADP] OS=Arabidopsis thaliana GN=ICDH PE=1 SV=1 [Swiss-Prot]
  • (Q9SLK0) NADP specific isocitrate dehydrogenase (EC 1.1.1.42) [athaliana3702.FASTAC.txt]
  • NADP specific isocitrate dehydrogenase [Arabidopsis thaliana]gi|12744346|gb|AAK06592.1| NADP-specific isocitrate dehydrogenase [Arabidopsis thaliana]gi|15221788|ref|NP_175836.1| isocitrate dehydrogenase, putative / NADP+ isocitrate dehydrogenase, putati [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Isocitrate dehydrogenase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ICDH | ICDH; isocitrate dehydrogenase (NADP+) | chr1:20287187-20290173 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • At1g54340 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • NADP specific isocitrate dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • NADP-specific isocitrate dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ICDH (isocitrate dehydrogenase); isocitrate dehydrogenase (NADP+)/ oxidoreductase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ICDH | isocitrate dehydrogenase | chr1:20283520-20286506 FORWARD LENGTH=416 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 416 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [IDA]
    plasma membrane [IDA]
    Biological Process: metabolic process [IEA][ISS]
    isocitrate metabolic process [IEA]
    Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [IEA]
    isocitrate dehydrogenase (NADP+) activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFEKIKVIN PVVEMDGDEM TRVIWKFIKD KLIFPFLELD IKYFDLGLPN RDFTDDKVTI  60
   61 ETAEATLKYN VAIKCATITP DEARVREFGL KKMWRSPNGT IRNILNGTVF REPIICRNIP 120
  121 RLVPGWTKPI CIGRHAFGDQ YRATDLIVNE PGKLKLVFEP SGSSQKTEFE VFNFTGGGVA 180
  181 LAMYNTDESI RAFAESSMYT AYQKKWPLYL STKNTILKIY DGRFKDIFQE VYEANWRSKY 240
  241 EAAGIWYEHR LIDDMVAYAM KSEGGYVWAC KNYDGDVQSD FLAQGYGSLG MMTSVLVCPD 300
  301 GKTIEAEAAH GTVTRHYRVH QKGGETSTNS IASIFAWSRG LAHRAKLDSN AALLSYTEKL 360
  361 EAACMGTVES GKMTKDLALL IHGAKVRRDQ YVNTEEFIDA VAWELKRRLL GNNSRL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..416] PSI-BLAST 132.0 NADP-dependent isocitrate dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • isocitrate dehydrogenase (NAD+) activity
    		•  5.9567768649084 bayes_pls_golite062009
  • isocitrate dehydrogenase activity
    		•  5.76817846591752 bayes_pls_golite062009
  • isocitrate dehydrogenase (NADP+) activity
    		•  3.47645456015586 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.74237430402883 bayes_pls_golite062009
  • catalytic activity
    		•  2.71251959637136 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  2.46799258909805 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  2.38235863668553 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.15484868227001 bayes_pls_golite062009
  • 3-isopropylmalate dehydrogenase activity
    		•  0.848289435089509 bayes_pls_golite062009
  • binding
    		•  0.530580225668688 bayes_pls_golite062009
  • protein binding
    		•  0.074256700284446 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle