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Protein Overview: ISPD_ARATH

General Information:
Name(s) found: ISPD_ARATH [Swiss-Prot]
Description(s) found:
Found 19 descriptions.
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  • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic OS=Arabidopsis thaliana GN=ISPD PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 302 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    plastid [NAS]
    Biological Process: isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway [TAS]
    Molecular Function: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMLQTNLGF ITSPTFLCPK LKVKLNSYLW FSYRSQVQKL DFSKRVNRSY KRDALLLSIK  60
   61 CSSSTGFDNS NVVVKEKSVS VILLAGGQGK RMKMSMPKQY IPLLGQPIAL YSFFTFSRMP 120
  121 EVKEIVVVCD PFFRDIFEEY EESIDVDLRF AIPGKERQDS VYSGLQEIDV NSELVCIHDS 180
  181 ARPLVNTEDV EKVLKDGSAV GAAVLGVPAK ATIKEVNSDS LVVKTLDRKT LWEMQTPQVI 240
  241 KPELLKKGFE LVKSEGLEVT DDVSIVEYLK HPVYVSQGSY TNIKVTTPDD LLLAERILSE 300
  301 DS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..76] PSI-BLAST 6.0 Crystal structure of UDP-N-acetylglucosamine pyrophosphorylase (Agx2) from Mus musculus at 2.50 A resolution
    2 View Details [77..302] PSI-BLAST 37.522879 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Arabidopsis thaliana

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
    		•  2.01680144494637 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • transferase activity
    		•  1.47184463413038 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.03393419806381 bayes_pls_golite062009
  • cytidylyltransferase activity
    		•  0.983416157001861 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.651454753851031 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  0.423789091098118 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.361674579616957 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.86

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle