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View Structure Prediction Details

Protein: ISPD_ARATH
Organism: Arabidopsis thaliana
Length: 302 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ISPD_ARATH.

Description E-value Query
Range
Subject
Range
gi|7434867, gi|3... - pir||S78498 probable glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Neisseria meningitidi...
181.0 [0..61] [299..22]

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Predicted Domain #1
Region A:
Residues: [1-76]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMLQTNLGF ITSPTFLCPK LKVKLNSYLW FSYRSQVQKL DFSKRVNRSY KRDALLLSIK  60
   61 CSSSTGFDNS NVVVKE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.0
Match: 1vm8A
Description: Crystal structure of UDP-N-acetylglucosamine pyrophosphorylase (Agx2) from Mus musculus at 2.50 A resolution
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [77-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSVSVILLAG GQGKRMKMSM PKQYIPLLGQ PIALYSFFTF SRMPEVKEIV VVCDPFFRDI  60
   61 FEEYEESIDV DLRFAIPGKE RQDSVYSGLQ EIDVNSELVC IHDSARPLVN TEDVEKVLKD 120
  121 GSAVGAAVLG VPAKATIKEV NSDSLVVKTL DRKTLWEMQT PQVIKPELLK KGFELVKSEG 180
  181 LEVTDDVSIV EYLKHPVYVS QGSYTNIKVT TPDDLLLAER ILSEDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 37.522879
Match: 1w77A
Description: 2C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) from Arabidopsis thaliana
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity 2.01680144494637 bayes_pls_golite062009
catalytic activity 1.88676710996045 bayes_pls_golite062009
transferase activity 1.47184463413038 bayes_pls_golite062009
nucleotidyltransferase activity 1.03393419806381 bayes_pls_golite062009
cytidylyltransferase activity 0.983416157001861 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 0.651454753851031 bayes_pls_golite062009
UDP-glycosyltransferase activity 0.423789091098118 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.361674579616957 bayes_pls_golite062009

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