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Protein Overview: MYST1_ARATH

General Information:
Name(s) found: MYST1_ARATH [Swiss-Prot]
Description(s) found:
Found 16 descriptions.
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  • Histone acetyltransferase of the MYST family 1 OS=Arabidopsis thaliana GN=HAM1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 445 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: chromatin assembly or disassembly [IEA]
    regulation of transcription [IEA]
    Molecular Function: nucleic acid binding [ISS]
    histone acetyltransferase activity [IDA][ISS]
    zinc ion binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSADTETA MIIATPASNH NNPATNGGDA NQNHTSGAIL ALTNSESDAS KKRRMGVLPL  60
   61 EVGTRVMCQW RDGKYHPVKV IERRKNYNGG HNDYEYYVHY TEFNRRLDEW IKLEQLDLDS 120
  121 VECALDEKVE DKVTSLKMTR HQKRKIDETH VEGHEELDAA SLREHEEFTK VKNIATIELG 180
  181 KYEIETWYFS PFPPEYNDCV KLFFCEFCLS FMKRKEQLQR HMRKCDLKHP PGDEIYRSST 240
  241 LSMFEVDGKK NKVYAQNLCY LAKLFLDHKT LYYDVDLFLF YILCECDDRG CHMVGYFSKE 300
  301 KHSEEAYNLA CILTLPPYQR KGYGKFLIAF SYELSKKEGK VGTPERPLSD LGLVSYRGYW 360
  361 TRILLDILKK HKGNISIKEL SDMTAIKAED ILSTLQSLEL IQYRKGQHVI CADPKVLDRH 420
  421 LKAAGRGGLD VDVSKMIWTP YKEQS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..157] PSI-BLAST 15.69897 Solution Structure of the Tudor Domain from Mouse Hypothetical Protein Homologous to Histone Acetyltransferase
    2 View Details [158..445] PSI-BLAST 116.0 No description for 2ou2A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription repressor activity
    		•  4.08500855631983 bayes_pls_golite062009
  • chromatin binding
    		•  3.84065302930105 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.64390820819794 bayes_pls_golite062009
  • methylated histone residue binding
    		•  3.42338304360938 bayes_pls_golite062009
  • binding
    		•  3.06758476214113 bayes_pls_golite062009
  • protein binding
    		•  2.66728689880621 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  2.46353586381231 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.19167058827256 bayes_pls_golite062009
  • DNA binding
    		•  2.05514577638135 bayes_pls_golite062009
  • histone binding
    		•  2.00388175060339 bayes_pls_golite062009
  • transcription activator activity
    		•  1.46529895769882 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.10020047862576 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.998957812785999 bayes_pls_golite062009
  • general transcriptional repressor activity
    		•  0.75184432495983 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.726970683178132 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.494788451379878 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.294457188332415 bayes_pls_golite062009
  • catalytic activity
    		•  0.14067200158938 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle