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Protein Overview: TPS4_ARATH

General Information:
Name(s) found: TPS4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75213722|sp|Q9T079.1|TPS4_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 4; AltName: Full=Trehalose-6-phosphate synthase 4; Short=AtTPS4 [NCBI NR]
  • pir||T05860 alpha,alpha-trehalose-phosphate synthase (UDP-forming) 56K chain homolog T29A15.40 - Arabidopsis thaliana [NCBI NR]
  • gi|7269609|emb|CAB81405.1| trehalose-6-phosphate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|4469006|emb|CAB38267.1| trehalose-6-phosphate synthase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15234194|ref|NP_194485.1| ATTPS4; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] [NCBI NR]
  • Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 4 OS=Arabidopsis thaliana GN=TPS4 PE=3 SV=1 [Swiss-Prot]
  • (Q9T079) Trehalose-6-phosphate synthase-like protein [athaliana3702.FASTAC.txt]
  • trehalose-6-phosphate synthase-like protein [Arabidopsis thaliana]gi|4469006|emb|CAB38267.1| trehalose-6-phosphate synthase-like protein [Arabidopsis thaliana]gi|7484800|pir||T05860 alpha,alpha-trehalose-phosphate synthase (UDP-forming) 56K chain homolo [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Alpha [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: TPS4, ATTPS4 | ATTPS4 (Arabidopsis thaliana trehalose phosphatase/synthase 4); transferase, transferring glycosyl groups | chr4:13755695-13759746 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • trehalose-6-phosphate synthase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATTPS4; transferase, transferring glycosyl groups [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATTPS4, TPS4 | trehalose-6-phosphatase synthase S4 | chr4:13755689-13759740 FORWARD LENGTH=795 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 795 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: trehalose biosynthetic process [ISS]
    Molecular Function: transferase activity, transferring glycosyl groups [ISS]
    alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARPRLLVVS MSLPVTAKRT GEESWSFTMS PGGLVSALLG LKEFETKWIG WPGVDVHDAI  60
   61 GKKTLSITLA EKGCIPVFLE EVCDQYYNGY CNNILWPIFH YLGTPPEYRN DATITYQSQY 120
  121 EAYKKANQIF FDVVKEHYEE GDVVWCHDYH VMLLPQYLKE YNSKMKVGWF LHTPFPSSEM 180
  181 YKTLPSRSDL LRSVLTADLV GFHTYDFARH FLNACMCILG VEATSEGIVD QGKVTRVAVF 240
  241 PIGIEPERFI NTSELSEVVQ YMKKFKNDFG GRKLILGVDR LDTIKGIPQK YQAFEKFLEE 300
  301 NAEWRGKVML LQIAVPTRNG IGEYQKIKDQ CHYHVGRING RFGSISSVPI IHLDCSIDFN 360
  361 QLCALYAITD VLLVTSLRDG MNLVSSEFIA CQKAEKGVLI LSEFAGAGQS LGAGAILVNP 420
  421 WNIKEVSSAI GEALNMSHEE KERKHKINFQ YVKTHSTQQW ADDFMKLTLT NILCSKLIEI 480
  481 TTSAELGAGL AATLELPEHD VIQQYSKSNN RLLILGFYGT LTQPMKNQER RGDGMNLELH 540
  541 PQLKERLKEL CSDPKTTVVV LSRSEKCILD KNFGEYNMWL AAENGMFLRH TSGEWVTRIP 600
  601 EHMNLEWIDG VKHVFKYFTE RTPGSYLETS EASLVWNYEN ADAEFGRAQA RDMLQHLWAG 660
  661 PISNASVDVV RGGQSVEVHA VGVTKGSAME RILGEIVHNK SMATPIDYVL CIGCFLGKDE 720
  721 DVYTFFEPEL TKKAKSLSSS GSDSPKKVSS TIVDLKGENY FSVAIGQTHT KARYFLDSSD 780
  781 DVVKLIGKLC THNNA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..485] PSI-BLAST 72.0 Trehalose-6-phosphate from E. coli bound with UDP-2-fluoro glucose.
    2 View Details [486..795] PSI-BLAST 25.69897 Crystal structure of trehalose-6-phosphate phosphatase related protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity
    		•  11.2045941324603 bayes_pls_golite062009
  • glucosyltransferase activity
    		•  8.25064561355471 bayes_pls_golite062009
  • UDP-glucosyltransferase activity
    		•  8.0463972704113 bayes_pls_golite062009
  • trehalose-phosphatase activity
    		•  7.58500038184065 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  3.70184884300914 bayes_pls_golite062009
  • catalytic activity
    		•  2.65148466065976 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  2.62403914335522 bayes_pls_golite062009
  • transferase activity
    		•  2.18054407163329 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  2.13085705769565 bayes_pls_golite062009
  • UDP-N-acetylglucosamine 2-epimerase activity
    		•  1.55280519670033 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  0.78952375993773 bayes_pls_golite062009
  • glycogen phosphorylase activity
    		•  0.607220464589157 bayes_pls_golite062009
  • binding
    		•  0.345236672370351 bayes_pls_golite062009
  • phosphorylase activity
    		•  0.296436712681472 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  0.253888301381021 bayes_pls_golite062009
  • protein binding
    		•  0.198267161626932 bayes_pls_golite062009
    2
    Term Confidence Notes
  • trehalose-phosphatase activity
    		•  3.78859922218487 bayes_pls_golite062009
  • transporter activity
    		•  2.28749015584769 bayes_pls_golite062009
  • hydrolase activity
    		•  2.23636068759523 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.17051010073814 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.14633664297706 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.05684652641195 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.05060633349756 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.84740904871745 bayes_pls_golite062009
  • catalytic activity
    		•  1.55296860681783 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.53201151596704 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.45647470429539 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.44542004757594 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.42792997211574 bayes_pls_golite062009
  • ATPase activity
    		•  1.40341876769691 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.352553895791 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
    		•  1.33388154652051 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.33292469269496 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.33065047107664 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.31602086166435 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.28050944646617 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.194344891491143 bayes_pls_golite062009
  • phosphatase activity
    		•  0.159899259988948 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.15490458026932 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.143980906464589 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.103902756538853 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.053543166906854 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.041293091790546 bayes_pls_golite062009
  • binding
    		•  0.0209333912048011 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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