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Protein Overview: GAE2_ARATH

General Information:
Name(s) found: GAE2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|8570451|gb|AAF76478.1|AC020622_12 Contains similarity to CAPI protein from Staphylococcus aureus gi|P39858 and contains a NAD dependent epimerase/dehydratase PF|01370 domain. ESTs gb|N97076, gb|AI997010 come from this gene. [Arabidopsis thaliana] [NCBI NR]
  • gi|75264107|sp|Q9LPC1.1|GAE2_ARATH RecName: Full=UDP-glucuronate 4-epimerase 2; AltName: Full=UDP-glucuronic acid epimerase 2 [NCBI NR]
  • pir||A86152 hypothetical protein F22M8.13 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|15217591|ref|NP_171702.1| GAE2 (UDP-D-GLUCURONATE 4-EPIMERASE 2); UDP-glucuronate 4-epimerase/ catalytic [Arabidopsis thaliana] [NCBI NR]
  • gi|12248041|gb|AAG50112.1|AF334734_1 putative nucleotide sugar epimerase [Arabidopsis thaliana] [NCBI NR]
  • UDP-glucuronate 4-epimerase 2 OS=Arabidopsis thaliana GN=GAE2 PE=2 SV=1 [Swiss-Prot]
  • (Q9LPC1) F22M8.13 protein (Putative NAD dependent epimerase/dehydratase protein) [athaliana3702.FASTAC.txt]
  • putative nucleotide sugar epimerase [Arabidopsis thaliana]gi|25518289|pir||A86152 hypothetical protein F22M8.13 [imported] - Arabidopsis thalianagi|8570451|gb|AAF76478.1| Contains similarity to CAPI protein from Staphylococcus aureus gi|P39858 and conta [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 NAD-dependent epimerase/dehydratase family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: GAE2 | GAE2 (UDP-D-GLUCURONATE 4-EPIMERASE 2); catalytic | chr1:346052-347356 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Contains similarity to CAPI protein from Staphylococcus aureus gi|P39858 and contains a NAD dependent epimerase/dehydratase PF|01370 domain. ESTs gb|N97076, gb|AI997010 come from this gene. [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • GAE2 (UDP-D-GLUCURONATE 4-EPIMERASE 2); NAD binding / catalytic [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative nucleotide sugar epimerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: GAE2 | UDP-D-glucuronate 4-epimerase 2 | chr1:346052-347356 FORWARD LENGTH=434 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 434 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: carbohydrate metabolic process [IEA]
    metabolic process [IEA]
    nucleotide-sugar metabolic process [ISS]
    cellular metabolic process [IEA]
    Molecular Function: UDP-glucuronate 4-epimerase activity [ISS]
    catalytic activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHLDDIPST PGKFKMMDKS PFFLHRTRWQ SSVAKLAFWS LVFFGLLFIF FYRSPISNPD  60
   61 SSRRSLRTYS WGGPAWEKRV RSSARVRTRN GVSVLVTGAA GFVGTHVSAA LKRRGDGVLG 120
  121 LDNFNDYYDT SLKRSRQALL ERSGVFIVEG DINDLSLLKK LFEVVPFTHV MHLAAQAGVR 180
  181 YAMENPGSYV HSNIAGFVNL LEVCKSANPQ PAIVWASSSS VYGLNTKVPF SEKDRTDQPA 240
  241 SLYAATKKAG EEIAHTYNHI YGLSLTGLRF FTVYGPWGRP DMAYFFFTRD ILKGKAISIF 300
  301 EGANHGTVAR DFTYIDDIVK GCLGALDTAE KSTGSGGKKR GAAQLRVFNL GNTSPVPVTD 360
  361 LVSILERLLK VKAKRNMMKL PRNGDVPFTH ANISSAQREF GYKPSTDLQT GLKKFVRWYL 420
  421 GYYKQGGKKV AAAA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..91] PSI-BLAST 6.69897 No description for 2fr0A was found.
    2 View Details [92..434] PSI-BLAST 85.0 dTDP-glucose 4,6-dehydratase (RmlB)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • binding
    		•  0.835119783772935 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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