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Protein Overview: MLH1_ARATH

General Information:
Name(s) found: MLH1_ARATH [Swiss-Prot]
Description(s) found:
Found 14 descriptions.
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  • DNA mismatch repair protein MLH1 OS=Arabidopsis thaliana GN=MLH1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 737 amino acids

    Gene Ontology:
    Cellular Component: nuclear chromatin [IDA]
    Biological Process: fruit development [IMP]
    pollen development [IMP]
    seed development [IMP]
    mismatch repair [ISS]
    seed germination [IMP]
    mitotic recombination [IMP]
    Molecular Function: protein binding, bridging [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDDSSLTAE MEEEESPATT IVPREPPKIQ RLEESVVNRI AAGEVIQRPV SAVKELVENS  60
   61 LDADSSSISV VVKDGGLKLI QVSDDGHGIR REDLPILCER HTTSKLTKFE DLFSLSSMGF 120
  121 RGEALASMTY VAHVTVTTIT KGQIHGYRVS YRDGVMEHEP KACAAVKGTQ IMVENLFYNM 180
  181 IARRKTLQNS ADDYGKIVDL LSRMAIHYNN VSFSCRKHGA VKADVHSVVS PSRLDSIRSV 240
  241 YGVSVAKNLM KVEVSSCDSS GCTFDMEGFI SNSNYVAKKT ILVLFINDRL VECSALKRAI 300
  301 EIVYAATLPK ASKPFVYMSI NLPREHVDIN IHPTKKEVSL LNQEIIIEMI QSEVEVKLRN 360
  361 ANDTRTFQEQ KVEYIQSTLT SQKSDSPVSQ KPSGQKTQKV PVNKMVRTDS SDPAGRLHAF 420
  421 LQPKPQSLPD KVSSLSVVRS SVRQRRNPKE TADLSSVQEL IAGVDSCCHP GMLETVRNCT 480
  481 YVGMADDVFA LVQYNTHLYL ANVVNLSKEL MYQQTLRRFA HFNAIQLSDP APLSELILLA 540
  541 LKEEDLDPGN DTKDDLKERI AEMNTELLKE KAEMLEEYFS VHIDSSANLS RLPVILDQYT 600
  601 PDMDRVPEFL LCLGNDVEWE DEKSCFQGVS AAIGNFYAMH PPLLPNPSGD GIQFYSKRGE 660
  661 SSQEKSDLEG NVDMEDNLDQ DLLSDAENAW AQREWSIQHV LFPSMRLFLK PPASMASNGT 720
  721 FVKVASLEKL YKIFERC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..395] PSI-BLAST 78.69897 DNA mismatch repair protein MutL
    2 View Details [396..737] PSI-BLAST 6.09691 TOPOISOMERASE RESIDUES 410-1202,


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle