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Protein Overview: RDR2_ARATH

General Information:
Name(s) found: RDR2_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T01920 probable RNA-directed RNA polymerase (EC 2.7.7.48) - Arabidopsis thaliana [NCBI NR]
  • gi|7267812|emb|CAB81214.1| putative RNA-directed RNA polymerase [Arabidopsis thaliana] [NCBI NR]
  • gi|4850292|emb|CAB43048.1| putative RNA-directed RNA polymerase [Arabidopsis thaliana] [NCBI NR]
  • gi|3600048|gb|AAC35535.1| similar to hypothetical proteins in Schizosaccharomyces pombe (GB:Z98533) and C. elegans (GB:Z48334 and Z78419) [Arabidopsis thaliana] [NCBI NR]
  • gi|15237051|ref|NP_192851.1| RDR2 (RNA-DEPENDENT RNA POLYMERASE 2); RNA-directed RNA polymerase [Arabidopsis thaliana] [NCBI NR]
  • RNA-dependent RNA polymerase 2 OS=Arabidopsis thaliana GN=RDR2 PE=1 SV=1 [Swiss-Prot]
  • (O82504) F2P3.11 protein (Putative RNA-directed RNA polymerase) [athaliana3702.FASTAC.txt]
  • putative RNA-directed RNA polymerase [Arabidopsis thaliana]gi|7267812|emb|CAB81214.1| putative RNA-directed RNA polymerase [Arabidopsis thaliana]gi|3600048|gb|AAC35535.1| similar to hypothetical proteins in Schizosaccharomyces pombe (GB:Z98533) and C. e [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 RNA-dependent RNA polymerase [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: SMD1, RDR2 | RDR2 (RNA-DEPENDENT RNA POLYMERASE 2); RNA-directed RNA polymerase | chr4:6780518-6784386 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative RNA-directed RNA polymerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • RDR2 (RNA-DEPENDENT RNA POLYMERASE 2); RNA-directed RNA polymerase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • similar to hypothetical proteins in Schizosaccharomyces pombe (GB:Z98533) and C. elegans (GB:Z48334 and Z78419) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: RDR2, SMD1 | RNA-dependent RNA polymerase 2 | chr4:6780522-6784390 FORWARD LENGTH=1133 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • RNA-dependent RNA polymerase 2 OS=Arabidopsis thaliana GN=RDR2 PE=3 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 1133 amino acids

    Gene Ontology:
    Cellular Component: nucleolus [IDA]
    Biological Process: gene silencing [IMP]
    long-distance posttranscriptional gene silencing [IMP]
    cell-cell signaling [IMP]
    posttranscriptional gene silencing [ISS]
    [NOT]response to salicylic acid stimulus [IEP]
    production of siRNA involved in RNA interference [IMP]
    RNA interference [IMP]
    Molecular Function: RNA-directed RNA polymerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVSETTTNRS TVKISNVPQT IVADELLRFL ELHLGEDTVF ALEIPTTRDN WKPRDFARVQ  60
   61 FTTLEVKSRA QLLSSQSKLL FKTHNLRLSE AYDDIIPRPV DPRKRLDDIV LTVGFPESDE 120
  121 KRFCALEKWD GVRCWILTEK RRVEFWVWES GDCYKIEVRF EDIIETLSCC VNGDASEIDA 180
  181 FLLKLKYGPK VFKRVTVHIA TKFKSDRYRF CKEDFDFMWI RTTDFSGSKS IGTSTCFCLE 240
  241 VHNGSTMLDI FSGLPYYRED TLSLTYVDGK TFASAAQIVP LLNAAILGLE FPYEILFQLN 300
  301 ALVHAQKISL FAASDMELIK ILRGMSLETA LVILKKLHQQ SSICYDPVFF VKTQMQSVVK 360
  361 KMKHSPASAY KRLTEQNIMS CQRAYVTPSK IYLLGPELET ANYVVKNFAE HVSDFMRVTF 420
  421 VEEDWSKLPA NALSVNSKEG YFVKPSRTNI YNRVLSILGE GITVGPKRFE FLAFSASQLR 480
  481 GNSVWMFASN EKVKAEDIRE WMGCFRKIRS ISKCAARMGQ LFSASRQTLI VRAQDVEQIP 540
  541 DIEVTTDGAD YCFSDGIGKI SLAFAKQVAQ KCGLSHVPSA FQIRYGGYKG VIAVDRSSFR 600
  601 KLSLRDSMLK FDSNNRMLNV TRWTESMPCF LNREIICLLS TLGIEDAMFE AMQAVHLSML 660
  661 GNMLEDRDAA LNVLQKLSGE NSKNLLVKML LQGYAPSSEP YLSMMLRVHH ESQLSELKSR 720
  721 CRILVPKGRI LIGCMDEMGI LEYGQVYVRV TLTKAELKSR DQSYFRKIDE ETSVVIGKVV 780
  781 VTKNPCLHPG DIRVLDAIYE VHFEEKGYLD CIIFPQKGER PHPNECSGGD LDGDQFFVSW 840
  841 DEKIIPSEMD PPMDYAGSRP RLMDHDVTLE EIHKFFVDYM ISDTLGVIST AHLVHADRDP 900
  901 EKARSQKCLE LANLHSRAVD FAKTGAPAEM PYALKPREFP DFLERFEKPT YISESVFGKL 960
  961 YRAVKSSLAQ RKPEAESEDT VAYDVTLEEA GFESFIETAK AHRDMYGEKL TSLMIYYGAA1020
 1021 NEEEILTGIL KTKEMYLARD NRRYGDMKDR ITLSVKDLHK EAMGWFEKSC EDEQQKKKLA1080
 1081 SAWYYVTYNP NHRDEKLTFL SFPWIVGDVL LDIKAENAQR QSVEEKTSGL VSI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..187] PSI-BLAST 5.39794 No description for 2cjkA was found.
    2 View Details [188..395] deduced N/A No confident structure predictions are available.
    3 View Details [396..1133] PSI-BLAST 133.0 No description for 2j7nA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle