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Protein Overview: RHM1_ARATH

General Information:
Name(s) found: RHM1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|62901057|sp|Q9SYM5.1|RHM1_ARATH RecName: Full=Probable rhamnose biosynthetic enzyme 1 [NCBI NR]
  • gi|4836876|gb|AAD30579.1|AC007260_10 Similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana] [NCBI NR]
  • pir||C96814 hypothetical protein T30F21.10 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|20148285|gb|AAM10033.1| similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana] [NCBI NR]
  • gi|15218420|ref|NP_177978.1| RHM1 (RHAMNOSE BIOSYNTHESIS 1); UDP-L-rhamnose synthase/ UDP-glucose 4,6-dehydratase/ catalytic [Arabidopsis thaliana] [NCBI NR]
  • gi|14596091|gb|AAK68773.1| Similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana] [NCBI NR]
  • Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1 OS=Arabidopsis thaliana GN=RHM1 PE=1 SV=1 [Swiss-Prot]
  • (Q9SYM5) T30F21.10 protein (Similar to dTDP-D-glucose 4,6-dehydratase) [athaliana3702.FASTAC.txt]
  • Similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana]gi|20148285|gb|AAM10033.1| similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana]gi|14596091|gb|AAK68773.1| Similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana]gi|254 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Probable rhamnose biosynthetic enzyme 1 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: RHM1, ROL1 | RHM1/ROL1 (RHAMNOSE BIOSYNTHESIS1); UDP-L-rhamnose synthase/ UDP-glucose 4,6-dehydratase/ catalytic | chr1:29555003-29557100 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • Similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • RHM1; NAD binding / catalytic [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • similar to dTDP-D-glucose 4,6-dehydratase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Probable rhamnose biosynthetic enzyme 1 [nr-271106-contam.fasta]
  • | Symbols: RHM1, ROL1, ATRHM1 | rhamnose biosynthesis 1 | chr1:29550110-29552207 FORWARD LENGTH=669 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • Probable rhamnose biosynthetic enzyme 1 OS=Arabidopsis thaliana GN=RHM1 PE=1 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 669 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    Biological Process: flavonol biosynthetic process [IMP]
    UDP-rhamnose biosynthetic process [IDA][IMP]
    nucleotide-sugar metabolic process [ISS]
    auxin efflux [IMP]
    Molecular Function: UDP-glucose 4,6-dehydratase activity [IDA]
    UDP-L-rhamnose synthase activity [IDA]
    catalytic activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASYTPKNIL ITGAAGFIAS HVANRLIRSY PDYKIVVLDK LDYCSNLKNL NPSKHSPNFK  60
   61 FVKGDIASAD LVNHLLITEG IDTIMHFAAQ THVDNSFGNS FEFTKNNIYG THVLLEACKV 120
  121 TGQIRRFIHV STDEVYGETD EDALVGNHEA SQLLPTNPYS ATKAGAEMLV MAYGRSYGLP 180
  181 VITTRGNNVY GPNQFPEKLI PKFILLAMRG QVLPIHGDGS NVRSYLYCED VAEAFEVVLH 240
  241 KGEVGHVYNI GTKKERRVND VAKDICKLFN MDPEANIKFV DNRPFNDQRY FLDDQKLKKL 300
  301 GWSERTTWEE GLKKTMDWYT QNPEWWGDVS GALLPHPRML MMPGGRHFDG SEDNSLAATL 360
  361 SEKPSQTHMV VPSQRSNGTP QKPSLKFLIY GKTGWIGGLL GKICDKQGIA YEYGKGRLED 420
  421 RSSLLQDIQS VKPTHVFNSA GVTGRPNVDW CESHKTETIR ANVAGTLTLA DVCREHGLLM 480
  481 MNFATGCIFE YDDKHPEGSG IGFKEEDTPN FTGSFYSKTK AMVEELLKEY DNVCTLRVRM 540
  541 PISSDLNNPR NFITKISRYN KVVNIPNSMT VLDELLPISI EMAKRNLKGI WNFTNPGVVS 600
  601 HNEILEMYRD YINPEFKWAN FTLEEQAKVI VAPRSNNEMD ASKLKKEFPE LLSIKESLIK 660
  661 YAYGPNKKT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..337] PSI-BLAST 78.522879 dTDP-glucose 4,6-dehydratase (RmlB)
    2 View Details [338..669] PSI-BLAST 37.39794 gdp-mannose-3', 5' -epimerase (arabidopsis thaliana), with gdp-alpha-d-mannose and gdp-beta-l-galactose bound in the active site.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  1.75109362865449 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.55012034958204 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009
    2
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • steroid dehydrogenase activity
    		•  1.75109362865449 bayes_pls_golite062009
  • steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.55012034958204 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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