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Protein Overview: WNK1_ARATH

General Information:
Name(s) found: WNK1_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75262294|sp|Q9CAV6.1|WNK1_ARATH RecName: Full=Serine/threonine-protein kinase WNK1; Short=AtWNK1; AltName: Full=Protein kinase with no lysine 1 [NCBI NR]
  • gi|20302596|dbj|BAB91125.1| Ser/Thr kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|15229843|ref|NP_187142.1| WNK1 (WITH NO LYSINE (K) 1); kinase/ protein kinase/ protein serine/threonine kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|12322854|gb|AAG51416.1|AC009465_16 putative mitogen activated protein kinase kinase; 49861-46888 [Arabidopsis thaliana] [NCBI NR]
  • Serine/threonine-protein kinase WNK1 OS=Arabidopsis thaliana GN=WNK1 PE=1 SV=1 [Swiss-Prot]
  • (Q9CAV6) Putative mitogen activated protein kinase kinase, 49861-46888 (Ser/Thr kinase) [athaliana3702.FASTAC.txt]
  • putative mitogen activated protein kinase kinase; 49861-46888 [Arabidopsis thaliana]gi|15229843|ref|NP_187142.1| protein kinase family protein [Arabidopsis thaliana]gi|20302596|dbj|BAB91125.1| Ser/Thr kinase [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Protein kinase family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ZIK4, WNK1 | WNK1 (WITH NO LYSINE (K) 1); kinase | chr3:1355090-1358063 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative mitogen activated protein kinase kinase; 49861-46888 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Ser/Thr kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • WNK1 (WITH NO LYSINE (K) 1); kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: WNK1, ZIK4, ATWNK1 | with no lysine (K) kinase 1 | chr3:1355084-1358057 FORWARD LENGTH=700 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 700 amino acids

    Gene Ontology:
    Cellular Component: membrane [IDA]
    Biological Process: protein amino acid phosphorylation [IDA]
    circadian rhythm [IEP]
    Molecular Function: protein kinase activity [IDA]
    protein serine/threonine kinase activity [ISS]
    kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNLSYLEPD YSEFVEVDPT GRYGRYNEVL GKGASKTVYR AFDEYEGIEV AWNQVKLYDF  60
   61 LQSPEDLERL YCEIHLLKTL KHKNIMKFYT SWVDTANRNI NFVTELFTSG TLRQYRLRHK 120
  121 RVNIRAMKHW CRQILRGLHY LHSHDPPVIH RDLKCDNIFV NGNQGEVKIG DLGLAAILRK 180
  181 SHAAHCVGTP EFMAPEVYEE AYNELVDIYS FGMCILEMVT FDYPYSECTH PAQIYKKVMS 240
  241 GKKPDALYKV KDPEVKCFIE KCLATVSLRV SARELLDDPF LRIDDGEFDL RSVDMEDSVG 300
  301 PLYRQPHHLP DYYNYPSNSS SLNRQYSNGN YPSNSSSLNR QYSNGYNSHH EYQNGWAYNP 360
  361 AETEETHGIE LFESRNNDDQ EEEKKSGNVD ITIKGKRRDD GGLFLRLRIA DKEGRVRNIY 420
  421 FPFDIETDTA LSVATEMVAE LDMDDHGVTK IANMIDGEIS SLVPSWRPGP EFEECLAAAA 480
  481 AANAASICNN CVSNRTSMGS VMDFLRTNPG ANVIQCCRNG CGETHGRFEE ITIRETEVRL 540
  541 RELWKLQQQQ ESRELSSIDS GHNHSEEEEE EEVLYEDPEN MFSCEAGNEI NHISGSGSFS 600
  601 FMPSKYCDEP SEKTENQVQQ ELRWLKAKCQ IELRDIQDEQ LKTRWPESGE EVEISPKDGF 660
  661 LGSVSGLGRE EDTVKEMFGE RLVPKCLKRT TSLPVDAIDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..288] PSI-BLAST 54.221849 Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension
    2 View Details [289..364] deduced N/A No confident structure predictions are available.
    3 View Details [365..700] PSI-BLAST 9.09691 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle