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Protein Overview: PABP6_ARATH

General Information:
Name(s) found: PABP6_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • Polyadenylate-binding protein 6 OS=Arabidopsis thaliana GN=PAB6 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 537 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: mRNA metabolic process [TAS]
    translational initiation [TAS]
    Molecular Function: translation initiation factor activity [ISS]
    RNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALVKTETQA LGNHQHSSRF GSLYVGDLSP DVTEKDLIDK FSLNVPVVSV HLCRNSVTGK  60
   61 SMCYAYINFD SPFSASNAMT RLNHSDLKGK AMRIMWSQRD LAYRRRTRTG FANLYVKNLD 120
  121 SSITSSCLER MFCPFGSILS CKVVEENGQS KGFGFVQFDT EQSAVSARSA LHGSMVYGKK 180
  181 LFVAKFINKD ERAAMAGNQD STNVYVKNLI ETVTDDCLHT LFSQYGTVSS VVVMRDGMGR 240
  241 SRGFGFVNFC NPENAKKAME SLCGLQLGSK KLFVGKALKK DERREMLKQK FSDNFIAKPN 300
  301 MRWSNLYVKN LSESMNETRL REIFGCYGQI VSAKVMCHEN GRSKGFGFVC FSNCEESKQA 360
  361 KRYLNGFLVD GKPIVVRVAE RKEDRIKRLQ QYFQAQPRQY TQAPSAPSPA QPVLSYVSSS 420
  421 YGCFQPFQVG TSYYYMGNQV PQMSGHQNIT TYVPAGKVPL KERRSMHLVY KHPAYPVAKR 480
  481 GAKQTLVFKG EVNRNLEAAT CSKATTSEEN RKEERRLTLS GKLSPEVKVE ESGKQLQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 48.69897 Poly(A)-binding protein
    2 View Details [89..211] PSI-BLAST 9.045757 NMR Structure of RRM2 from Human Polypyrimidine Tract Binding Protein Isoform 1 (PTB1)
    3 View Details [212..297] FFAS03 3.69 NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
    4 View Details [298..381] PSI-BLAST 22.154902 No description for 2d9pA was found.
    5 View Details [382..537] PSI-BLAST 3.30103 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • RNA binding
    		•  5.15097136329571 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.92126426323641 bayes_pls_golite062009
  • mRNA binding
    		•  4.05281507540116 bayes_pls_golite062009
  • binding
    		•  3.64400841800969 bayes_pls_golite062009
    		• 2.60920363363072 bayes_pls_golite062009
  • protein binding
    		•  2.17260848225967 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.92450390013691 bayes_pls_golite062009
  • DNA binding
    		•  1.8021593476478 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.46469774223879 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  1.36691748240059 bayes_pls_golite062009
  • transcription factor activity
    		•  1.15127506309683 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.998305828880243 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.824614388276642 bayes_pls_golite062009
  • mRNA 5'-UTR binding
    		•  0.625848256054783 bayes_pls_golite062009
  • translation repressor activity, nucleic acid binding
    		•  0.461000905454505 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.383589644462932 bayes_pls_golite062009
  • translation regulator activity
    		•  0.38120065819101 bayes_pls_golite062009
  • structural molecule activity
    		•  0.166336846372115 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.128616879457381 bayes_pls_golite062009
    3
    Term Confidence Notes
  • RNA binding
    		•  4.74219150342477 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.65259034341669 bayes_pls_golite062009
  • mRNA binding
    		•  3.63162433534903 bayes_pls_golite062009
  • binding
    		•  3.48033873254013 bayes_pls_golite062009
    		• 2.38034004712143 bayes_pls_golite062009
  • protein binding
    		•  2.10850948869511 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.94691250607537 bayes_pls_golite062009
  • DNA binding
    		•  1.80828042019548 bayes_pls_golite062009
  • transcription factor activity
    		•  1.17242427495624 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  1.08300488237934 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.00459347347517 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.960399311787502 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.462558743683805 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.327072171076297 bayes_pls_golite062009
  • mRNA 5'-UTR binding
    		•  0.271234585816403 bayes_pls_golite062009
  • translation regulator activity
    		•  0.246220338604608 bayes_pls_golite062009
  • structural molecule activity
    		•  0.175217083426707 bayes_pls_golite062009
  • translation repressor activity, nucleic acid binding
    		•  0.147208072406136 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.0127733116412899 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle