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Protein Overview: MAOP4_ARATH

General Information:
Name(s) found: MAOP4_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||E96828 probable malate oxidoreductase, 93001-96525 [imported] - Arabidopsis thaliana [NCBI NR]
  • gi|22655472|gb|AAM98328.1| At1g79750/F19K16_27 [Arabidopsis thaliana] [NCBI NR]
  • gi|16974613|gb|AAL31209.1| At1g79750/F19K16_27 [Arabidopsis thaliana] [NCBI NR]
  • gi|15219980|ref|NP_178093.1| ATNADP-ME4 (NADP-malic enzyme 4); malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)/ malic enzyme/ oxidoreductase, acting on NADH or NADPH, NAD or NADP as acceptor [Arabidopsis thaliana] [NCBI NR]
  • gi|12324574|gb|AAG52235.1|AC011717_3 putative malate oxidoreductase; 93001-96525 [Arabidopsis thaliana] [NCBI NR]
  • NADP-dependent malic enzyme 4, chloroplastic OS=Arabidopsis thaliana GN=NADP-ME4 PE=1 SV=1 [Swiss-Prot]
  • (Q9CA83) Putative malate oxidoreductase (At1g79750/F19K16_27) (Malic enzyme) [athaliana3702.FASTAC.txt]
  • At1g79750/F19K16_27 [Arabidopsis thaliana]gi|16974613|gb|AAL31209.1| At1g79750/F19K16_27 [Arabidopsis thaliana]gi|12324574|gb|AAG52235.1| putative malate oxidoreductase; 93001-96525 [Arabidopsis thaliana]gi|15219980|ref|NP_178093.1| malate oxidoreducta [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 The malic enzyme (EC 1.1.1.40) encoded by AtNADP-ME4 is localized to chloroplasts [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATNADP-ME4 | ATNADP-ME4 (NADP-MALIC ENZYME 4); malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)/ malic enzyme/ oxidoreductase, acting on NADH or NADPH, NAD or NADP as acceptor | chr1:30012548-30016072 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • malic enzyme/ oxidoreductase, acting on NADH or NADPH, NAD or NADP as acceptor [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g79750/F19K16_27 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative malate oxidoreductase; 93001-96525 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATNADP-ME4, NADP-ME4 | NADP-malic enzyme 4 | chr1:30007655-30011179 REVERSE LENGTH=646 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 646 amino acids

    Gene Ontology:
    Cellular Component: chloroplast [IDA]
    Biological Process: malate metabolic process [ISS][TAS]
    fatty acid biosynthetic process [TAS]
    Molecular Function: zinc ion binding [IDA]
    malic enzyme activity [ISS]
    malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity [IDA]
    oxidoreductase activity, acting on NADH or NADPH, NAD or NADP as acceptor [ISS]
    cobalt ion binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISLTPSLFL NKTVVPGCST RLSLRQPRTI ITPPASLRVF SSLGSNQDPT GSVLIETTAT  60
   61 SSSSLETSAA DIVPKSTVSG GVQDVYGEDA ATEDMPITPW SLSVASGYTL LRDPHHNKGL 120
  121 AFSHRERDAH YLRGLLPPTV ISQDLQVKKI MHTLRQYQVP LQKYMAMMDL QETNERLFYK 180
  181 LLIDHVEELL PVIYTPTVGE ACQKYGSIFL RPQGLFISLK EKGKIHEVLR NWPEKNIQVI 240
  241 VVTDGERILG LGDLGCQGMG IPVGKLSLYT ALGGVRPSAC LPVTIDVGTN NEKLLNDEFY 300
  301 IGLRQRRATG EEYSELMHEF MTAVKQNYGE KVVIQFEDFA NHNAFDLLAK YGTTHLVFND 360
  361 DIQGTASVVL AGLIAALRFV GGSLSDHRFL FLGAGEAGTG IAELIALEIS KKSHIPLEEA 420
  421 RKNIWLVDSK GLIVSSRKES IQHFKKPWAH DHEPIRELVD AVKAIKPTVL IGTSGVGQTF 480
  481 TQDVVETMAK LNEKPIILSL SNPTSQSECT AEEAYTWSQG RAIFASGSPF APVEYEGKTF 540
  541 VPGQANNAYI FPGFGLGLIM SGTIRVHDDM LLAASEALAE ELMEEHYEKG MIYPPFRNIR 600
  601 KISARIAAKV AAKAYELGLA TRLPQPKELE QCAESSMYSP SYRSYR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] MSA 1.091986 View MSA. No confident structure predictions are available.
    2 View Details [113..646] PSI-BLAST 1000.0 Crystal structure of a human malic enzyme


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.74

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle