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Protein Overview: NDK3_ARATH

General Information:
Name(s) found: NDK3_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T01877 nucleoside-diphosphate kinase (EC 2.7.4.6) - Arabidopsis thaliana [NCBI NR]
  • gi|7267799|emb|CAB81202.1| nucleoside diphosphate kinase 3 (ndpk3) [Arabidopsis thaliana] [NCBI NR]
  • gi|6225753|sp|O49203.1|NDK3_ARATH RecName: Full=Nucleoside diphosphate kinase III, chloroplastic/mitochondrial; Short=NDP kinase III; Short=NDPK III; Short=NDK III; Flags: Precursor [NCBI NR]
  • gi|4539375|emb|CAB40069.1| nucleoside diphosphate kinase 3 (ndpk3) [Arabidopsis thaliana] [NCBI NR]
  • gi|3513740|gb|AAC33956.1| contains similarity to nucleoside diphosphate kinases (Pfam: NDK.hmm, score: 301.12) [Arabidopsis thaliana] [NCBI NR]
  • gi|2829275|gb|AAC00512.1| nucleoside diphosphate kinase 3 [Arabidopsis thaliana] [NCBI NR]
  • gi|17065632|gb|AAL33810.1| putative nucleoside diphosphate kinase 3 [Arabidopsis thaliana] [NCBI NR]
  • gi|15237018|ref|NP_192839.1| NDPK3 (NUCLEOSIDE DIPHOSPHATE KINASE 3); ATP binding / nucleoside diphosphate kinase [Arabidopsis thaliana] [NCBI NR]
  • gi|14334560|gb|AAK59688.1| putative nucleoside diphosphate kinase ndpk3 [Arabidopsis thaliana] [NCBI NR]
  • Nucleoside diphosphate kinase III, chloroplastic/mitochondrial OS=Arabidopsis thaliana GN=NDPK3 PE=1 SV=1 [Swiss-Prot]
  • (O49203) Nucleoside diphosphate kinase III, chloroplast/mitochondrial precursor (EC 2.7.4.6) (NDK III) (NDP kinase III) (NDPK III) [athaliana3702.FASTAC.txt]
  • putative nucleoside diphosphate kinase 3 [Arabidopsis thaliana]gi|14334560|gb|AAK59688.1| putative nucleoside diphosphate kinase ndpk3 [Arabidopsis thaliana]gi|4539375|emb|CAB40069.1| nucleoside diphosphate kinase 3 (ndpk3) [Arabidopsis thaliana]gi|726 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Nucleoside diphosphate kinase III, chloroplast/mitochondrial precursor [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: NDPK3 | NDPK3 (NUCLEOSIDE DIPHOSPHATE KINASE 3); ATP binding / nucleoside diphosphate kinase | chr4:6732776-6734294 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • contains similarity to nucleoside diphosphate kinases (Pfam: NDK.hmm, score: 301.12) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • putative nucleoside diphosphate kinase 3 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Nucleoside diphosphate kinase III, chloroplast/mitochondrial precursor (NDK III) (NDP kinase III) (NDPK III) [nr-271106-contam.fasta]
  • putative nucleoside diphosphate kinase ndpk3 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • nucleoside diphosphate kinase 3 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • nucleoside diphosphate kinase 3 (ndpk3) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • NDPK3 (NUCLEOSIDE DIPHOSPHATE KINASE 3); ATP binding / nucleoside diphosphate kinase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: NDPK3 | nucleoside diphosphate kinase 3 | chr4:6732780-6734298 REVERSE LENGTH=238 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 238 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    mitochondrial inner membrane [IDA]
    plastid [IDA]
    Biological Process: response to oxidative stress [IDA]
    Molecular Function: ATP binding [ISS]
    zinc ion binding [IDA]
    nucleoside diphosphate kinase activity [ISS]
    cobalt ion binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQICRSAS KAAKSLLSSA KNARFFSEGR AIGAAAAVSA SGKIPLYASN FARSSGSGVA  60
   61 SKSWITGLLA LPAAAYMIQD QEVLAAEMER TFIAIKPDGV QRGLISEIIS RFERKGFKLV 120
  121 GIKVIVPSKD FAQKHYHDLK ERPFFNGLCD FLSSGPVIAM VWEGDGVIRY GRKLIGATDP 180
  181 QKSEPGTIRG DLAVTVGRNI IHGSDGPETA KDEISLWFKP QELVSYTSNS EKWLYGDN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..83] deduced N/A No confident structure predictions are available.
    2 View Details [84..238] PSI-BLAST 68.0 Structure and mutational analysis of a plant mitochondrial nucleoside diphosphate kinase: identification of residues involved in serine phosphorylation and oligomerization.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  9.54806938681864 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  8.99343206813136 bayes_pls_golite062009
  • nucleoside diphosphate kinase activity
    		•  6.31603417387406 bayes_pls_golite062009
  • kinase activity
    		•  5.17632668597727 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.81683227683584 bayes_pls_golite062009
  • tubulin binding
    		•  3.91203457981165 bayes_pls_golite062009
  • transferase activity
    		•  3.88584335567051 bayes_pls_golite062009
  • microtubule binding
    		•  3.30486676956703 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.90440302787538 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.33936391947568 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.14345344254908 bayes_pls_golite062009
  • DNA binding
    		•  1.9929237581784 bayes_pls_golite062009
  • binding
    		•  1.77213317402453 bayes_pls_golite062009
  • catalytic activity
    		•  1.54275558650196 bayes_pls_golite062009
  • protein binding
    		•  1.44203715518441 bayes_pls_golite062009
  • transcription factor activity
    		•  1.25823661686679 bayes_pls_golite062009
  • gamma-tubulin binding
    		•  0.715852577944201 bayes_pls_golite062009
  • ATP binding
    		•  0.642661537717629 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.611368256550302 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.594323192037838 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.548739243763112 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.548674300422543 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.538092730319695 bayes_pls_golite062009
  • nucleotide binding
    		•  0.532504383462049 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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