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Protein Overview: HIS8_ARATH

General Information:
Name(s) found: HIS8_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|30697915|ref|NP_568981.2| ATHDH (HISTIDINOL DEHYDROGENASE); histidinol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • gi|29427983|sp|Q9C5U8.1|HISX_ARATH RecName: Full=Histidinol dehydrogenase, chloroplastic; Short=HDH; Flags: Precursor [NCBI NR]
  • gi|23505959|gb|AAN28839.1| At5g63890/MGI19_9 [Arabidopsis thaliana] [NCBI NR]
  • gi|14532514|gb|AAK63985.1| AT5g63890/MGI19_9 [Arabidopsis thaliana] [NCBI NR]
  • gi|13516461|dbj|BAB40445.1| histidinol dehydrogenase [Arabidopsis thaliana] [NCBI NR]
  • Histidinol dehydrogenase, chloroplastic OS=Arabidopsis thaliana GN=HDH PE=2 SV=1 [Swiss-Prot]
  • Histidinol dehydrogenase, chloroplastic OS=Arabidopsis thaliana GN=HISN8 PE=2 SV=1 [Swiss-Prot]
  • (Q9C5U8) Histidinol dehydrogenase, chloroplast precursor (EC 1.1.1.23) (HDH) [athaliana3702.FASTAC.txt]
  • At5g63890/MGI19_9 [Arabidopsis thaliana]gi|13516461|dbj|BAB40445.1| histidinol dehydrogenase [Arabidopsis thaliana]gi|14532514|gb|AAK63985.1| AT5g63890/MGI19_9 [Arabidopsis thaliana]gi|30697915|ref|NP_568981.2| histidinol dehydrogenase, putative / HDH, [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Splice Isoform 1 of Histidinol dehydrogenase, chloroplast precursor [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: ATHDH | ATHDH (HISTIDINOL DEHYDROGENASE) | chr5:25582826-25585330 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • histidinol dehydrogenase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • ATHDH (HISTIDINOL DEHYDROGENASE) [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • AT5g63890/MGI19_9 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Histidinol dehydrogenase, chloroplast precursor (HDH) [nr-271106-contam.fasta]
  • At5g63890/MGI19_9 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATHDH, HISN8, HDH | histidinol dehydrogenase | chr5:25565600-25568104 REVERSE LENGTH=466 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 466 amino acids

    Gene Ontology:
    Cellular Component: chloroplast stroma [IDA]
    chloroplast [IDA]
    Biological Process: pollen development [IMP]
    response to UV [IEP]
    Molecular Function: histidinol dehydrogenase activity [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNLSRLSL LSSPRISIST HAPRKGYVCC SMKSYRLSEL SSSQVDSLKS RPRIDFSSIF  60
   61 ATVNPIIDAV RSNGDNAVKE YTERFDKVQL NKVVEDMSEL SVPELDSNVK EAFDVAYDNI 120
  121 YAFHLAQKST EKSVENMKGV RCKRVSRSIG SVGLYVPGGT AVLPSTALML AIPAQIAGCK 180
  181 TVVLATPPSK DGSICKEVLY CAKRAGVTHI LKAGGAQAIA AMAWGTDSCP KVEKIFGPGN 240
  241 QYVTAAKMIL QNSEAMVSID MPAGPSEVLV IADEHASPVY IAADLLSQAE HGPDSQVVLV 300
  301 VVGDSVDLNA IEEEIAKQCK SLPRGEFASK ALSHSFTVFA RDMIEAISFS NLYAPEHLII 360
  361 NVKDAEKWEG LIENAGSVFI GPWTPESVGD YASGTNHVLP TYGYARMYSG VSLDSFLKFM 420
  421 TVQSLTEEGL RNLGPYVATM AEIEGLDAHK RAVTLRLKDI EAKQLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..466] PSI-BLAST 172.0 L-histidinol dehydrogenase HisD

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  2.32012109012499 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.31275077585879 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.24875477727877 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  2.22720948878196 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.42

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle