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Protein Overview: HMA2_ARATH

General Information:
Name(s) found: HMA2_ARATH [Swiss-Prot]
Description(s) found:
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  • pir||T08987 probable cadmium-transporting ATPase (EC 3.6.1.-) F6G3.140 - Arabidopsis thaliana [NCBI NR]
  • gi|7269911|emb|CAB81004.1| cadmium-transporting ATPase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|4938487|emb|CAB43846.1| cadmium-transporting ATPase-like protein [Arabidopsis thaliana] [NCBI NR]
  • gi|15234620|ref|NP_194740.1| HMA2; cadmium-transporting ATPase [Arabidopsis thaliana] [NCBI NR]
  • gi|12229675|sp|Q9SZW4.1|AHM3_ARATH RecName: Full=Putative cadmium/zinc-transporting ATPase 3 [NCBI NR]
  • Cadmium/zinc-transporting ATPase HMA2 OS=Arabidopsis thaliana GN=HMA2 PE=2 SV=1 [Swiss-Prot]
  • Cadmium/zinc-transporting ATPase 3 OS=Arabidopsis thaliana GN=HMA2 PE=2 SV=1 [Swiss-Prot]
  • (Q9SZW4) Potential cadmium/zinc-transporting ATPase 3 (EC 3.6.3.3) (EC 3.6.3.5) [athaliana3702.FASTAC.txt]
  • cadmium-transporting ATPase-like protein [Arabidopsis thaliana]gi|4938487|emb|CAB43846.1| cadmium-transporting ATPase-like protein [Arabidopsis thaliana]gi|12229675|sp|Q9SZW4|AHM3_ARATH Potential cadmium/zinc-transporting ATPase 3gi|7488066|pir||T08987 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Putative cadmium/zinc-transporting ATPase 3 [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: HMA2 | HMA2 (Heavy metal ATPase 2); cadmium-transporting ATPase | chr4:14720259-14724583 REVERSE [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • cadmium-transporting ATPase-like protein [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • HMA2; cadmium-transporting ATPase [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • Putative cadmium/zinc-transporting ATPase 3 [nr-271106-contam.fasta]
  • | Symbols: HMA2, ATHMA2 | heavy metal atpase 2 | chr4:14720253-14724577 REVERSE LENGTH=951 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 951 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [IEA]
    endomembrane system [IEA]
    Biological Process: metabolic process [IEA]
    metal ion transport [IEA]
    ATP biosynthetic process [IEA]
    Molecular Function: cadmium-transporting ATPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASKKMTKSY FDVLGICCTS EVPLIENILN SMDGVKEFSV IVPSRTVIVV HDTLILSQFQ  60
   61 IVKALNQAQL EANVRVTGET NFKNKWPSPF AVVSGILLLL SFFKYLYSPF RWLAVAAVVA 120
  121 GIYPILAKAV ASLARFRIDI NILVVVTVGA TIGMQDYTEA AVVVFLFTIA EWLQSRASYK 180
  181 ASAVMQSLMS LAPQKAVIAE TGEEVEVDEL KTNTVIAVKA GETIPIDGVV VDGNCEVDEK 240
  241 TLTGEAFPVP KLKDSTVWAG TINLNGYITV NTTALAEDCV VAKMAKLVEE AQNSKTETQR 300
  301 FIDKCSKYYT PAIILISICF VAIPFALKVH NLKHWVHLAL VVLVSACPCG LILSTPVATF 360
  361 CALTKAATSG LLIKGADYLE TLAKIKIVAF DKTGTITRGE FIVMDFQSLS EDISLQSLLY 420
  421 WVSSTESKSS HPMAAAVVDY ARSVSVEPKP EAVEDYQNFP GEGIYGKIDG KEVYIGNKRI 480
  481 ASRAGCLSVP DIDVDTKGGK TIGYVYVGET LAGVFNLSDA CRSGVAQAMK ELKSLGIKIA 540
  541 MLTGDNHAAA MHAQEQLGNA MDIVRAELLP EDKSEIIKQL KREEGPTAMV GDGLNDAPAL 600
  601 ATADIGISMG VSGSALATET GNIILMSNDI RRIPQAIKLA KRAKRKVVEN VVISITMKGA 660
  661 ILALAFAGHP LIWAAVLADV GTCLLVILNS MLLLSDKHKT GNKCYRESSS SSVLIAEKLE 720
  721 GDAAGDMEAG LLPKISDKHC KPGCCGTKTQ EKAMKPAKAS SDHSHSGCCE TKQKDNVTVV 780
  781 KKSCCAEPVD LGHGHDSGCC GDKSQQPHQH EVQVQQSCHN KPSGLDSGCC GGKSQQPHQH 840
  841 ELQQSCHDKP SGLDIGTGPK HEGSSTLVNL EGDAKEELKV LVNGFCSSPA DLAITSLKVK 900
  901 SDSHCKSNCS SRERCHHGSN CCRSYAKESC SHDHHHTRAH GVGTLKEIVI E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..658] PSI-BLAST 115.0 No description for 3b8eA was found.
    2 View Details [659..743] PSI-BLAST 112.0 Proton ATPase
    3 View Details [744..951] PSI-BLAST 17.30103 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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