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Protein Overview: lkh1

General Information:
Name(s) found: lkh1 / SPAC1D4.11c [Sanger Pombe]
Description(s) found:
Found 14 descriptions.
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  • dual specificity protein kinase Lkh1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 690 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: regulation of barrier septum formation [IMPLink to PubMed article]
    regulation of cell separation during cytokinesis [IMPLink to PubMed article]
    cellular response to oxidative stress [IMPLink to PubMed article]
    negative regulation of flocculation [IMPLink to PubMed article]
    protein amino acid phosphorylation [ICLink to PubMed article]
    negative regulation of filamentous growth [IMPLink to PubMed article]
    regulation of fungal-type cell wall organization [IMPLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    protein tyrosine kinase activity [IEA]
    protein serine/threonine kinase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHSLKRRRNH APDWQDFYKN GVPQEVIVIE DSASPRLTPN LPPPFSVHQL QSFVPPQPPS  60
   61 SSSPSTTGTV AVPINGANAV YPSTNSVSLP QSYDPWLDAN GVVPLPHDVA SHPSYMVQSP 120
  121 TSYHACSNNQ SPFPHSHHPP LHNPLPVSCQ PVLRPPPVPQ VPSHWYPVSL PSPNLPHQPI 180
  181 SKPPVIPNLP KLQVHPNRLP HPIHNHPYSS PTSYPPPLCP ATYCPSNPPQ LAPATAIAPS 240
  241 SQSSQHKSVN YSVTPSSINN HTAVPLSPTL AVWLPMTQPT FQPPSANVYQ PASNANQVIT 300
  301 PVSISDYRPP KKRKRAAWPP YKKVDRVNVP VVHDTTAFDP STFDDDDGHY KVVPNSKFAN 360
  361 RYTVVRLLGH GTFGKVIQCY DQSTGRHCAI KVTRAIPKYR EASLIELRVL QTIAHSDPTN 420
  421 ENKCIQLRDY FDYRKHICIV TDLFGWSVFD FLKNNNYIPF PLKHIQMLSQ QLFKSVAFLH 480
  481 SLGLVHTDLK PENVLLVSNA SRTIRLPYRN YSQKVLNSCE IRLIDFGSAT FEDEYHSSVV 540
  541 STRHYRAPEI ILGLGWSYPC DVWSIGCILV ELFTGQALFQ THEDSEHLCM MEKILGPFDR 600
  601 NMISRSSRTS QRFFKSDGKV RYPLSNTPKK SINYLQSLQT LEQIFAVSSP EVALLLDLLK 660
  661 KVFVYDPKRR ITAKEALWHP FFTQPISSNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..185] deduced N/A No confident structure predictions are available.
    2 View Details [186..358] deduced N/A No confident structure predictions are available.
    3 View Details [359..690] PSI-BLAST 74.69897 Crystal structure of human CLK1 in complex with 10Z-Hymenialdisine


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle