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Protein Overview: CE35897

General Information:
Name(s) found: CE35897 [WormBase]
Description(s) found:
Found 13 descriptions.
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  • WBGene00010912 status:Partially_confirmed UniProt:Q7JMN1 protein_id:CAE48508.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 794 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEALink to PubMed article]
    Biological Process: purine nucleotide biosynthetic process [IEALink to PubMed article]
    metabolic process [IEALink to PubMed article]
    'de novo' IMP biosynthetic process [IEALink to PubMed article]
    GMP biosynthetic process [IEALink to PubMed article]
    Molecular Function: ATP binding [IEALink to PubMed article]
    GMP synthase (glutamine-hydrolyzing) activity [IEALink to PubMed article]
    catalytic activity [IEALink to PubMed article]
    anthranilate synthase activity [IEALink to PubMed article]
    phosphoribosylformylglycinamidine synthase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFSSQVYPC SPKRVKIGAR QSKRHCRNLP SELQRAKRTK AVSKVSEHTM KRSSSMLDIN  60
   61 EDSQHSTNKA PPPKKAPEDR FDSANMNASG SHVTLVENLP VEKVSSGERI AILDFGAQYG 120
  121 KVIDRRVREL LVQSEMFPLN TTARTLIELG GFKGIIISGG PNSVFEPEAP SIDPEIFTCG 180
  181 LPVLGICYGF QLMNKLNGGT VTREHIREDG ACEIQVDTSV HLFNGLHKTE TVLLTHGDSV 240
  241 SEATVAPDFK VMAKSGHHVA GICNENRKLY GVQFHPEVDL TTNGTKMFEN FLFKVVGCCG 300
  301 NFTIQNREQS CISEINSIVG DKKVLVMVSG GVDSAVCAAL LRRALGPNRV TAIHIDNGFM 360
  361 RHEESDAVEK SLAALDLPIH RYNFGTTFRS STEHCKDGEV ALDECDDPEM KRKIIGNTFI 420
  421 RVKDVIMKDL NINHDEYFLA QGTLRPDLIE SASALASGHA DTIKTHHNDT FLVRELRKLG 480
  481 KVVEPLKDFH KDEVRELGKD LGLPESIVQR HPFPGPGLAI RILCASDKRP ELMFNGPMYN 540
  541 GDVQGRIIDV TEQFLNSAIN PSQGIYEHLQ FEQARNNVLL SLSERDRQLA EQQTFQISAH 600
  601 ILPIKTVGVQ GDARSYSYAV ALSTEQRPIP WKLLFAYASV IPKLFHGVNR VVYAFGSKIE 660
  661 FSIEDLTRTY LVPHIVTKLQ MADHIANNIL FGRVAASDGT QLPNVGHKIQ QMPVVLLPVD 720
  721 FDRDRDMIGS YRHSIVLRPF VTSDFMTGQA AIPGVHLPEE TLIEMDKAIR TNVLGISRVL 780
  781 LDMTCKPPGT TEWE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..107] PSI-BLAST 68.522879 Carbamoyl phosphate synthetase, small subunit N-terminal domain; Carbamoyl phosphate synthetase, small subunit C-terminal domain
    2 View Details [108..664] PSI-BLAST 135.0 GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain
    3 View Details [665..794] FFAS03 6.12 GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • imidazoleglycerol-phosphate synthase activity
    		•  0.270391651600004 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle