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Protein Overview: pde-2

General Information:
Name(s) found: pde-2 / CE35750 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00011146 locus:pde-2 status:Confirmed UniProt:P30645 protein_id:CAE47469.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 734 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: signal transduction [IEALink to PubMed article]
    Molecular Function: catalytic activity [IEALink to PubMed article]
    3',5'-cyclic-nucleotide phosphodiesterase activity [IEALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLELRRNSSP SSAHPSPQTN CQNSQRGDGL HHHHHEAASG STCCGGMTVF TGANAAKSSN  60
   61 EPAGSASPTV WRKTSHPPLH FNNNETRNRN LQMQLKNRGT KDDWGASLRY DIEEPTSSGL 120
  121 LELLPDVPIV RKLSRPLVKM DDQDDACSVA SNESDRTVLS PLVPMSIFDQ FLCLTNNLSA 180
  181 LISCIIAEAK KNTEAEDYAV FLHDEDNKQM VLFNNETMLM TGKKFDMGYG IVGKVASTMR 240
  241 TMNIRDVSRC PFFNEEIDEQ FSIKARNLIA FPLIDSSCSL IGVIVLYNKE NGFSRHDEKY 300
  301 IKRFSYFVAN SIAHAILAKQ IEEVRTRIHM VEEFKIQGED AVIEEVDIMR LVNDPLRDWR 360
  361 YFSQNFADFS FPPRSVGENH FHRASMMFFE DLGFSMLYKL NKRKLSYLVL RVSAGYRPVP 420
  421 YHNWSHAFAV THFCWLTLRT DAIRRALSDM ERLSLLIACL CHDIDHRGTT NSFQMQSLQK 480
  481 TPLSVLYSTE GSVLERHHFA QTIKLLQQEE CSILENLPAA DFRTIVNTIR EVILATDISA 540
  541 HLRKQERIKT MISEGYNPMS FDHRYLLMCL VMTASDLSDQ AKNFHNAKRI AENIYLEFFA 600
  601 QGDLELQLGV KPLEMMDRTN AYVPTVQIDF LFKIGVPVFQ LLASVVPEGR TTSEAIDANH 660
  661 LCWVALDEEV RNNPSATKYT RVFARRESRT EDIRSSAKAR PKSCRNCFKT VRACICKRKC 720
  721 SSNTRYFGSS FRWI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] FFAS03 0.955 No description for 2p06A was found.
    2 View Details [101..340] PSI-BLAST 22.0 3',5'-cyclic nucleotide phosphodiesterase 2A, GAF A and GAF B domains
    3 View Details [341..734] PSI-BLAST 71.30103 The Crystal Structure of the Phosphodiesterase 2A Catalytic Domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.0826290321540933 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle