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Protein Overview: lon-2

General Information:
Name(s) found: lon-2 / CE35426 [WormBase]
Description(s) found:
Found 15 descriptions.
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  • WBGene00003056 locus:lon-2 status:Confirmed UniProt:Q18530 protein_id:CCD67078.1 [WormBase]
    • Organism: Caenorhabditis elegans
    Length: 508 amino acids

    Gene Ontology:
    Cellular Component: cell surface [IDALink to PubMed article]
    Biological Process: negative regulation of multicellular organism growth [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    embryonic development ending in birth or egg hatching [IMPLink to PubMed article]
    negative regulation of transforming growth factor beta receptor signaling pathway [IGILink to PubMed article]
    Molecular Function: growth factor binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFRWLILFV LLYRSVLPAE EVVVVDILTN STSLEEPTEE YTCDCNTDDL IQKGNYTLTV  60
   61 EVKNMQVRLV EPFRDAIAFT TGEKKHLLDF IRFVTLREVR STYPLLLNYT DFLNSFDEMI 120
  121 GTFRNILTTE NAISLTGIKY EVSTAVQKFL SAILPDMFLC LSVGKCRTVP LDYHNCMMAS 180
  181 TKHWSVYLGN TPNKMAMTIS EAIYRYRKVE FLLVDMHKQL MNAHNLTLSH ECLQEYVHTL 240
  241 PCNCTMAGIT PCHTSCSNSM EKCFGKFSRE WAAKLHLMRN MTSTKKSFLD EFLSLKKTIF 300
  301 SVIRIFIERK SYVYAEHVFN SCGPLGEMII HPSKHSVHFQ SPGPFVSRGD GAVRELQLSA 360
  361 KTWDRLGRKI CDHSGVVLNP TMCYDGTKVI SIDHDLLPIT KDVRPRPMMD WIEKKNEKKA 420
  421 NVEGSASNPL WDDEDSEDFD GSGSGMPPVI DRNPVKAIIQ EDHPKNIDLS TNPKGPSVIV 480
  481 TEKEIQPDGS TTSSILICVI IVAVIKLF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..249] deduced N/A No confident structure predictions are available.
    2 View Details [250..401] deduced N/A No confident structure predictions are available.
    3 View Details [402..508] MSA 1.002954 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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