Protein Overview: vab-10

General Information:
Name(s) found:	vab-10 / CE35151 [WormBase]
Description(s) found: SHOW ONLY BEST	WBGene00006876 locus:vab-10 status:Confirmed UniProt:G5EFM4 protein_id:CAD90187.2 [WormBase] gi\|71997204\|ref\|NP_001021854.1\| Variable ABnormal morphology family member (vab-10) [Caenorhabditis elegans] [NCBI NR] gi\|33300867\|emb\|CAD90176.2\| C. elegans protein ZK1151.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|33300495\|emb\|CAD90183.2\| C. elegans protein ZK1151.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|33300473\|emb\|CAD90187.2\| C. elegans protein ZK1151.1b, confirmed by transcript evidence [Caenorhabditis elegans] [NCBI NR] gi\|27763989\|emb\|CAD44324.1\| VAB-10B protein [Caenorhabditis elegans] [NCBI NR] [wormpep111.fasta] Hypothetical protein ZK1151.1b [Caenorhabditis elegans]gi\|33300867\|emb\|CAD90176.2\| Hypothetical protein ZK1151.1b [Caenorhabditis elegans]gi\|33300495\|emb\|CAD90183.2\| Hypothetical protein ZK1151.1b [Caenorhabditis elegans]gi\|27763989\|emb\|CAD44324.1\| VAB [nrdb_11152004_Chlamydomonas] CE35151 WBGene00006876 locus:vab-10 status:Confirmed TR:Q7K7B6 protein_id:CAD90187.2 [wormpep150.fasta] 35151 WBGene00006876 locus:vab-10 status:Confirmed TR:Q7K7B6 protein_id:CAD90187.2 [wormpep130-phg-ecoli-orf-rand.fasta] locus:vab-10 status:Confirmed TN:CAD90187 protein_id:CAD90187.2 [wormpep115.fasta.reversed] CE35151 WBGene00006876 locus:vab-10 status:Confirmed UniProt:Q7K7B6_CAEEL protein_id:CAD90187.2 [WormBase_C-elegans_193_07-31-2008_con_reversed.fasta] CE35151 WBGene00006876 locus:vab-10 status:Confirmed UniProt:Q7K7B6_CAEEL protein_id:CAD90187.2\| [wormORF-contam.fasta] Hypothetical protein ZK1151.1b [Caenorhabditis elegans] [nr-271106-contam.fasta] Variable ABnormal morphology family member (vab-10) [Caenorhabditis elegans] [nr-271106-contam.fasta] VAB-10B protein [Caenorhabditis elegans] [nr-271106-contam.fasta] [wormpep210-phg-orf-LaDeana-ecoli-contam.fasta.nr] CE35151 WBGene00006876 locus:vab-10 status:Confirmed UniProt:Q7K7B6 protein_id:CAD90187.2 [wormbase_c-elegans_2.11_01-10-2010_reversed.fasta] CE35151 WBGene00006876 locus:vab-10 status:Confirmed UniProt:G5EFM4 protein_id:CAD90187.2 [wormbase_c_elegans_ws231_03-13-2012_reversed.fasta] Isoform of G5EDD3, Uncharacterized protein OS=Caenorhabditis elegans GN=vab-10 PE=1 SV=1 [CAEEL.fasta.20160308]
Organism:	Caenorhabditis elegans
Length:	4944 amino acids
Gene Ontology:
Cellular Component:	intracellular organelle [IDA] basal plasma membrane [IDA] membrane [IEA] intermediate filament [IDA] apical plasma membrane [IDA] proteinaceous extracellular matrix [IEA]
Biological Process:	cell cycle arrest [IEA] DNA repair [IEA] hermaphrodite genitalia development [IMP] signal transduction [IEA] locomotion [IMP ] embryonic development ending in birth or egg hatching [IMP ] post-embryonic body morphogenesis [IMP ] positive regulation of growth rate [IMP] protein amino acid dephosphorylation [IEA] cell adhesion [IEA] gamete generation [IMP] blood coagulation [IEA] reproduction [IMP] growth [IMP] chemotaxis [IEA] locomotory behavior [IMP ] nematode larval development [IMP ] morphogenesis of an epithelium [IMP] gastrulation with mouth forming first [IMP]
Molecular Function:	actin binding [IEA] protein tyrosine phosphatase activity [IEA] calcium ion binding [IEA] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVGERYRSHH AVDPSDAQEK EVLDHYELNR EKYNDERDNV QKKTFTKWVN KHLSKTDHKI  60
   61 DDLFVDLRDG YALIALLEAL TGERIQKENG YTRFHRIQNV QYCLDFLKKK NIKLVNIRPE 120
  121 DIVEGNGKLT LGLIWTIILN FQVSVIRQRL LLESSQHEQM SAKHTTTNSQ VSLHGSDATS 180
  181 ARDALLQWAR RVTAGYPRVN VNNFSSSWRD GLAFNAILHR YRSSAIDWNK ISSDSVSNTE 240
  241 RLNNAFAAAD REFGVERLLD AEDVDTNNPD EKSIITYVSS LYNALPHEPE MSRLQKVQEE 300
  301 YIEEAYEWRE WVVRAIQLVD DRHLQGTASE LIYELQRFRE DDLPPREEQK RRLTLVYEHL 360
  361 EKVMRSTELF AIPHELSAPE LQRVWNELQN SIDRRFDVLE RHRIQEGNSN DLLSRLARGI 420
  421 GITNEKLDLI LKRIEDVEAR VDTSPPAAVE RTVSEIVDDL NALESPIARF FEDVEELKSM 480
  481 QHPEANDFYK QVYGLHQRRT TYLDRLTNQI LVRLGVRTDS LHKENQQRLE NMRKTSFSRV 540
  541 EECIEWVRVR MEKLTTMEFL EDLETLEHVF EQHKFDNRDI QDFRQNVDEC IARQAEVSAE 600
  601 DTYEYCELLR VLESEYQQLR DLSAGRMLDL DSLIAFVRAA QLELIWVSER ESIEVTRNWS 660
  661 DIKQLDLPML TNYYKQLLHE MELREKQYND VHNQGAALLN QGHPAIRVIE VYLRQMQSQW 720
  721 DWLLALSKCL EEHLRDALNL KSFMEEASDA EAWIQEQSVR LENNYNRTDF SLEEGERFLR 780
  781 ELDEIKEILN KYHQVLMALT ERCASISPLW QRGERIPHPI KVTALCDYSD ENVTIKAGDD 840
  841 VYLLDNSDLI KWTIRDISGA EGQVPSVVFR IPPTDARLTA LLNRLLQQFE KLKKLWDKKH 900
  901 RMVRFNMVLN TMRTIQGWDL DTFNSIDPDQ RDAIMKALND DANKLLSELD PNDPLALRLR 960
  961 EELRRTNEHF WNLLNASQKP PEPDWASQYD QKMAELLKKL EEAWRELNDA VGKPISRSPE1020
 1021 DLERVIHAHK RFEDALQALD SDVANVKELF RQLPNPTPTQ RVNHDRLNGL WDDLWDLSRM1080
 1081 YVERIKVLES VLNGMVEVAD IVRQHEITLN SFDDLPAALD KLRGHHSQLL EINMVLKVSK1140
 1141 LGAQNEHFSQ QQTVIDQLNR NVALLRQHVS RTRINEGHHP DVDAIEDEVQ KLNVRWENVN1200
 1201 SQIASRLLAV ESALQIQMVY RSEYETEMSW LDTVEETINR LRKPEELRPE QYQQQLDMLI1260
 1261 AEYTNLQEHT QAIEHVNKEG GRFIHEAKIF DAKLGQYSDG IVGIHGPGIK SEFRRTKPQP1320
 1321 KNGSQIVTEE LELLNRRFAQ LSSLILERRN TMQVLIQNWK RQKQENVTQV VSFREAEVSG1380
 1381 MMTDLTRFRQ EIFTTHLTFN SNPESIDAAT KNVQNVKQSL DSWRDRIKER LDEIDRLCTE1440
 1441 EGDSLTPEQY SALREMRRQL ADEYDTVLRT VEGIHTRLNI LSALLIEFSS VTSSMQSWMT1500
 1501 DRTRLAGDIR HKSGDPMRID EARFEAKSLM DEVIREESRL KTIGASVLKI EQEISAMRDD1560
 1561 VRASGSTDDV GISVDEVYET RRRVEDDYMQ LLRQCQDLIS FQNRLHAMND EHSEQARRAD1620
 1621 EWLQMLQNDV EDVDQDPRFQ RDEDRIQRIE ELNRMAAGGS SQLDDAEQAS RRLLTALEGT1680
 1681 NVANDVRARH EELANLRRGK HQKVIDRLSQ NMMEAASRKA EAEGVKQAVE NLRQWSEQTA1740
 1741 QRTRQPVQLP LTELDLHEAR KDEQVLHGEI ENRLALIEEL EKKAADVGDH ASLAELQECK1800
 1801 MKLKRSNSDL KGLRDNIFDA INGLQTVNSE GETLSRAVDS AGAKIRSARL PEAQSEVEAL1860
 1861 QDQADNLERI TNNLCNIPNV TRTEPVIQKS KDLRKRVDSC AQELDARMGK LAELESLDAE1920
 1921 FDGAKNKLSS FIGAFDDELK GLEKVSIDKE KLAEQRRQTQ DLVDKHSEGN AILDDVEAIA1980
 1981 QKVTAEDPSK TGSAQKSVGE LGARLQRQAS ELKARGDKIN KLDSKATSFA ESEAAVLGYI2040
 2041 EKQKDQLSTG FPVPATKEGV KSQLLDLERM NKTGKEEQRR VDDARHSARE LAREASVEKE2100
 2101 VQDMNQREKK LLDEWEDLAD QFDAVRSRAN KAEQVLNECA QMEKYIGAKK NMLEGIGAPS2160
 2161 TEPGVAKANR AQIQSMKAET EGEKSALEHV NSLANELIAD GGANVEELMK KMDRLNRKWH2220
 2221 SLESGLDENA GRVEEAAKLG QELKDIQKEL RKELGELESN VEKASAMSSN DIGDQLATLD2280
 2281 SLKSRFGGVD KALEKLKGIL EATEELEVDA TNRAEIQEQL ETTQKKADEL ERKIENVKKA2340
 2341 ALNAQNEGLE LEKKLDELIG TVNSAENELE LAAPIAAESL KLADELKRAE ELFQKLIENE2400
 2401 GDVSLIRAKV AEELKKKPDA ELKKKLELLY QKWPKALGAA RDRKDLVSKA GDLVKQFGDQ2460
 2461 VQALEQRLQG DQAELDELLA SDKAHDPEVC DALKLVELTM ARRLADVDAL NAVMNRIESS2520
 2521 APGPDANRLR RRADTLSDDA KGMAKKARTA ADLAQRKQGL AKKFERLCDE VSQFTENQKA2580
 2581 EIQDAIEKDL LNAERVQSKL NKIDDFWSSN SRELKNVGDE IKIDATPEDA QAVDTKLAEL2640
 2641 QAGIDGLLAT LQEQNVHLEE KREQANRVQS ESQKAAGKIN SLVAEIADLD PIGRSRDELQ2700
 2701 KQKKEVVELA GDLGSAQTKM LELGAEWEAA LGAGIVAQPV FEMNRAATDE LNKLAARAGK2760
 2761 RLAQREKKIT ETEDEIDKLH ADADQIVGAL EAIAKDEALQ GAPSQLLDPK QVSEKVRQLK2820
 2821 ESLKPVGEKM DAFNTDCKLL IKTAGPESDT KELDSLLKKV GDAYSDVVGK VSDKEMSVDA2880
 2881 AVQQQGKVED AYRALLNWLE ETEEMMENRK KPSADAKVAK AQLHDYEVLM KHVEDKKPSV2940
 2941 DGFKAMIEKI VAEASSDEEK KALGNKNAQI EDRYKDLLNS AVDRQRKLLD AVDLAERLQE3000
 3001 VTIPLDSWLQ SADKRLQALA KVPITVEKAE EMIGEQEALQ DELEHKSDDL KDVLEIAPML3060
 3061 ASLVSVEDAN SISGQVNQLE ARARALDAGI TNMRPLLESF LQQIQDFTLD AEDMTQFVGE3120
 3121 TEVKLGELDE LPIEPDDLVE QTNILAEIAV SIADRDEMMA NIFEVGKQLA IQGEPEEALI3180
 3181 AQKKLDDLKF RYADLMTSAD EKIALLAKAI PLSEGFHEGF DTVMQVLEDM DRDLQTIDEE3240
 3241 DPETQAELIF LLEEDISQKM RPSVDELTAL SNQLQVLCSA DKADELQTNT IAMNKLVNSV3300
 3301 ADRVARRAER IEMASKQSRA VLDDLQYLIE WFSAARERIL EGAPPSLDLE VLKSQLKHQR3360
 3361 ITNEEASANK VQFRNVAGEA KKVARQLGME GNEANEKISD TVDEGKELVE EVMALCADRT3420
 3421 ETLERALALM EQLTSQFDEL NKWLDQMDAE LQASPSVTTA TPAAELREMH DHNEELARMV3480
 3481 AAYRPIIEGF KSDVGSLHEV LAEDQAPLLE SVAGELVQGY EEVREAVRAR GHAIDNMMGA3540
 3541 TIGFGERLET LVANLQGAAD RLRENEGISA DPSVLESRLA ENRSIVESLR DKQNAYDALK3600
 3601 QTASELLASA PEGDAAAGDV ENKLNRLEKL WKEIEREAVD RGVLLEDVLD KAKHFWSELD3660
 3661 SCQKAVDDLR NRLELVEPAT GHPEQLADQQ EIMAQVASEM ERARPRIEAL SIAGKQLADY3720
 3721 VPDDEKAVIE NQVANVRGGF STITGLFAEK KRDLIAAMEE AMTFHGDLQE LLKWLDMAEQ3780
 3781 KLLKMSPVEH AKHMTEIEQL LKELHTFKDE VHERGVAKEQ VVATALQLAA DAPPHLAATV3840
 3841 RQPVADLNTR WSRLNAALAE REHKLENLML QMGKLASTIA QLTAWMDKTR ATLKDIAPPK3900
 3901 NAVNLRDIEI AQCKLVVLSN DIHAHQDSVN AVNRAAQKYI QTSGALDAET SDSLKSMNLK3960
 3961 WEDIQKVLES LAFDMEVAKK EAENVGGEVE KWQRWLEETE SALLSTKPTG GLPETAEFQL4020
 4021 DEFKALKLDV EHNASPLEAH LHATEQHLKE EPQDADTWLS KTHGAMKTKW NKVKELLVDR4080
 4081 EKKLQVAYEQ AVALESALND MEDWIIAAER KLTDQPSISR LPDVIEKQLA EHESWMEEVA4140
 4141 GRKMAMTKHQ ASGVHMQYYC EKKDAIPIKN RLVSLKHRVE KISGRTAERA KQLAVTRDEV4200
 4201 ATWQDGLHDL EHFISDVLVK IAPEPNTTSS LEKLKAKLEE VKEAQRDVTA KQTLFDVTRK4260
 4261 RGIGLAERAT RSEYKQISMT NEKMSKKWAE MLKKLRDRLR EAEQAVLEGG AFEESMNDLE4320
 4321 SWVDDELERY QKAEHEPVFA DIDGVRALVD EESRRSAERK TKENGVKTVV KKADALMASG4380
 4381 VDEKDSIAQA KERLVEKWNQ VEEAARHRGN SIKEAEQAAE EFDAKTHALL DWLAVEEQKL4440
 4441 KASGLDEVEG VKQEMDEAKG RYQECLKKGE EILSKCQPAA EPILRNWMRV VEARWKEVSE4500
 4501 KVDEREFTLL EQEQKAKEQN EQIEKLAKFA AQKREELNRM IEQPPAQDLD TMEQNICDFA4560
 4561 NLDSELREQQ PEVDAACKSA KKGARNPAAE MLSTEWKKLW LDAMGLQSSL DNQKALLEEM4620
 4621 KRLEGWKWED WKERYVEWND HAKARVNDLF RRIDRLHTGN VPRQVFIDGI IGSKFPTSRL4680
 4681 EMAKVADRFD KGDGMINAKE FINALRFDAS NRNAKPQTDT EKITHEIELQ KKTCSCCTPY4740
 4741 QIEKISENHY RFGDTHIKRM VRILRSTVMV RVGGGWESLD EFLHKHDPCR AKGRLNINMF4800
 4801 PEARPIHALD SMRSFTKNRH GKQLPTTGTP GPIMKIREKT DRSVPMSGGL GGTAGYTVTT4860
 4861 DSHRHTDARP SRIPRAPSDM SAGRLSRVGS VSNSKNSIVD SSTPSRPESR ASSDAGDRQT4920
 4921 RIPSLRARKG QRYIPQGPSS SSSK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	hcp-1	hcp1 IP from december2004	Cheeseman, I.M., et al. (2005)
View Run	hcp-2	hcp2 ip from december	Cheeseman, I.M., et al. (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Protein Overview: vab-10

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: